59 results
Pancytopenia - Differential Diagnosis

Congenital Diseases:
• GATA2 deficiency
• Fanconi’s anemia
• Wiskott-Aldrich syndrome
• Ribosomopathy or telomeropathy

Cancer:
• Leukemia
• Lymphoma

Inflammatory
Congenital Diseases ... deficiency • Fanconi’s anemia ... Wiskott-Aldrich syndrome ... Antibody-mediated hemolysis Nutritional ... #Diagnosis #Hematology
Red Blood Cell (RBC) Morphology Atlas
 • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Myelodysplastic syndrome ... , Bleeding gastric ... Hemolytic uremic syndrome ... key #diagnosis #differential ... #hematology
Causes of Iron Deficiency
 • Inadequate Intake: Vegetarian/vegan diet, Malnutrition
 • Increased Body Needs: Infants/preschoolers, Pregnancy,
Pregnancy, EPO treatment ... Loss (without anaemia ... Hookworm infection, Bleeding ... Iron #Deficiency #differential ... diagnosis #causes #nutrition
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Low Mean Corpuscular Volume (<80
Causes of Anemia ... Volume (MCV) - Differential ... 80-100 fL) • Bleeding ... Classification #Differential ... Algorithm #Causes #Hematology
Risk Factors and Signs of Copper Deficiency
Risk Factors:
 • Gastrointestinal: Previous upper bowel resection/bariatric surgery, Inflammatory
diarrhoea, Short bowel syndrome ... dental fixatives, Treatment ... • Nutritional: ... /jejunal nutrition ... Haematological: Anaemia
Pancytopenia - Workup and Differential Diagnosis Algorithm
Consumption Disorders
 1. Autoimmune Mediated Pancytopenia
 2. Splenic Sequestration
Peripheral Destruction
HLH syndrome 5. ... Drugs Nutritional ... Acquired Aplastic Anemia ... Metastatic Disease ... Diagnosis #Algorithm #Hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
Thrombocytosis - Differential ... disorders • Celiac disease ... effect following treatment ... Iron deficiency anemia ... Thrombocytosis #Differential
Pancytopenia - Workup and Differential Diagnosis Algorithm
Consumption Disorders
 1. Autoimmune Mediated Pancytopenia
 2. Splenic Sequestration
Peripheral Destruction
HLH syndrome 5 ... Drugs Nutritional ... Acquired Aplastic Anemia ... Metastatic Disease ... Diagnosis #Algorithm #Hematology
Refeeding Syndrome Overview

What Is It?
	• Electrolyte/fluid shifts caused by initiation of nutrition in severely malnourished patient.
Refeeding Syndrome ... initiation of nutrition ... due to chronic disease ... hyperparathyroidism Treatment ... #Nutrition #Differential
Causes of Iron Deficiency
 • Diet: ↓ Intake, e.g. vegan, Malnutrition, Polyphenol / tannins, ↓ Vitamin
Celiac, Enteritis, Bleeding ... : IBD, Chronic disease ... Deficiency #Causes #differential ... #diagnosis #anemia ... #nutrition