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diagnosis algorithm pancytopenia causes deficiency liver management oncology workup activation aplastic atlas b12 bariatric bruising bypass cancer chemistry complications effusion
Pancytopenia - Differential Diagnosis Congenital Diseases: • GATA2 deficiency • Fanconi’s anemia • Wiskott-Aldrich syndrome • Ribosomopathy or telomeropathy Cancer: • Leukemia • Lymphoma Inflammatory
Pancytopenia - Differential ... deficiency • Fanconi’s anemia ... Wiskott-Aldrich syndrome ... Antibody-mediated hemolysis Nutritional ... #Diagnosis #Hematology
Pancytopenia - Workup and Differential Diagnosis Algorithm Consumption Disorders 1. Autoimmune Mediated Pancytopenia 2. Splenic Sequestration Peripheral Destruction
HLH syndrome 5. ... Drugs Nutritional ... Acquired Aplastic Anemia ... Non-Nutritional ... Diagnosis #Algorithm #Hematology
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Myelodysplastic syndrome ... Liver diseases, Bleeding ... Hemolytic uremic syndrome ... key #diagnosis #differential ... #hematology
Pancytopenia - Workup and Differential Diagnosis Algorithm Consumption Disorders 1. Autoimmune Mediated Pancytopenia 2. Splenic Sequestration Peripheral Destruction
HLH syndrome 5 ... Drugs Nutritional ... Acquired Aplastic Anemia ... Non-Nutritional ... Diagnosis #Algorithm #Hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
→ Refer to hematology ... hemolysis, deficiency anemia ... Rebound effect from treatment ... Kawasaki, Nephrotic syndrome ... Diagnosis #Algorithm #hematology
Causes of Thrombocytopenia - Differential Diagnosis Framework Decreased Production: - Drugs (chemo, yang, sulfa, acetaminophen, NSAIDs, quinine,
Thrombocytopenia - Differential ... Malaria, babesia - Nutritional ... antiphospholipid syndrome ... sequestration: - Cirrhosis ... Diagnosis #Framework #hematology
Causes of Pleural Effusion - Differential Diagnosis Algorithm Transudate - Hydrostatic • Congestive heart failure • Constrictive
Pleural Effusion - Differential ... - Oncotic • Cirrhosis ... • Nephrotic syndrome ... • Asbestos • Uremia ... Diagnosis #Algorithm #Hepatology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Constitutional Syndromes ... ecchymoses, mucosal bleeding ... Constitutional Syndromes ... Treatment: ... #oncology #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
unusual bruising or bleeding ... are caused by bleeding ... Platelet Disorders • Nutritional ... blood count with differential ... #diagnosis #hematology
Causes of Anemia in Cirrhosis - Differential Diagnosis Framework LOW RETIC INDEX - ↓ PRODUCTION • Vitamin
in Cirrhosis - ... Differential Diagnosis ... Destruction: Zieve's syndrome ... #Cirrhosis #Differential ... #Diagnosis #Hepatology
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