15 results
Cirrhosis leading to Chronic Liver Failure - Clinical Signs and Symptoms

#Cirrhosis #LiverFailure #Signs #Symptoms #PhysicalExam #Findings
Cirrhosis leading ... to Chronic Liver ... and Symptoms #Cirrhosis ... PhysicalExam #Findings #Diagnosis ... #Hepatology
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework
Mild (<100-500): 
 • NAFLD
 • Cirrhosis
 •
Elevated Liver Function ... - Differential Diagnosis ... • NAFLD • Cirrhosis ... #Differential #Diagnosis ... #hepatology #transaminitis
Disorders of the Hepatic and Mesenteric Circulation

Platelets in Cirrhosis
Hypercoagulability in Cirrhosis
Bleeding in Cirrhosis
Portal Vein Thrombosis (PVT)
Mesenteric
Platelets in Cirrhosis ... Bleeding in Cirrhosis ... Circulation #Disorders #Hepatology ... #Gastroenterology ... #diagnosis #Management
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis
Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... - Differential Diagnosis ... Algorithm for Transaminitis ... Congenital, Others, Cirrhosis ... #Algorithm #diagnosis
CHA2DS2VASc vs HAS-BLED scores for stroke risk and bleed risk on anticoagulation

C	Congestive Heart Failure	1

H	Hypertension	1

A2	Age >75	2

D	Diabetes Mellitus	1

S2	Stroke,
Abnormal renal/liver ... (cirrhosis, bilirubin ... S Stroke 1 B Bleeding ... #AFib #Diagnosis ... #Hematology
Patterns of Liver Injury
Transaminase Levels:
  > 50x normal - Ischemic Hepatitis
  > 20x normal
Patterns of Liver ... CMV), Alcoholic cirrhosis ... #Injury #hepatology ... #LFTs #transaminitis ... #differential #diagnosis
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic Liver ... those with CLD (± cirrhosis ... #Failure #Cirrhosis ... #Hepatology #gastroenterology ... #management #diagnosis
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm
Thrombocytopenia - Quantitative Defect
 • Decreased Production
 •
Causes of Bleeding ... - Differential Diagnosis ... - Acquired • Anticoagulation ... Iatrogenic) • Liver ... Algorithm #Causes #Hematology
HAS-BLED Score - Risk of Major Bleeding in 1 Year
Characteristics (1 point each)
 • Hypertension: Baseline
Risk of Major Bleeding ... transplant • Liver ... disease: Cirrhosis ... #anticoagulation ... #diagnosis #stratification
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
hepatitis: < 1 • Cirrhosis ... RBC (hemolysis, bleeding ... #chemistry #diagnosis ... #differential #Hepatology ... #transaminitis