21 results
Inherited Non-hemolytic Disorders of Hyperbilirubinemia 

== Disorders of Conjugation ==
Gilbert Syndrome:
 • 5-10% of the population
• Type I CN is ... and stress may cause ... • Disorder is ... #hepatology #diagnosis ... #gastroenterology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
purpura to mucosal bleeding ... ↑ AST ↑ ALT ↑ bilirubin ... Treatment: • Corticosteroids ... Diagnosis #Management #Hematology ... #Rheumatology
Irritable Bowel Syndrome (IBS) - Management
Global IBS Symptoms:
  - Limited trial low FODMAP diet
Irritable Bowel Syndrome ... Rifaximin- up to 3 courses ... and Hepatology ... Irritable #Bowel #Syndrome ... #treatment
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... old, ~10,000 new cases ... cell transplant is ... only curative treatment ... #hematology #oncology
Hemophilia - Diagnosis and Management
Diagnosis:
 • Consistent bleeding history (unless screening for disease in family members
disease) • aPTT is ... normal in mild cases ... Classify severity Treatment ... by a hemophilia treatment ... #hematology
Irritable Bowel Syndrome (IBS) - Diagnosis and Management Summary
Diagnosis:
 • Use a positive diagnostic strategy with
Irritable Bowel Syndrome ... for diagnosis Treatment ... Rifaximin- up to 3 courses ... and Hepatology ... #treatment
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
Treatment: ... Treat primary cause ... Coagulation #diagnosis #causes ... #treatment #management ... #hematology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... autoantibodies that will cause ... inflammation, leading ... Puncture, EEG Treatment ... CNS #neurology #rheumatology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
group of disorders caused ... unusual bruising or bleeding ... skin that are caused ... by bleeding (petechiae ... #diagnosis #hematology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Algorithm Vascular Causes ... vein: Budd-chiari syndrome ... are normal, ALP is ... • Gilbert's syndrome ... RBC (hemolysis, bleeding