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differential management coagulation prolonged abnormal algorithm thrombocytopenia aflp blood bruising comparison disorders hellp monkeypox obstetrics pregnancy product ptt reactions treatment
Causes of Prolonged PT (INR), Prolonged PTT • Prolonged PT (INR), Prolonged PTT • Prolonged PT
Causes of Prolonged ... PTT, Normal PT ... (INR) - Bleeding ... #Differential #Diagnosis ... #Hematology #coagulation
How to Evaluate an Abnormal APTT Step 1: Is the PT or APTT Artifactually Prolonged? Step 2: Is
Step 1: Is the PT ... Prolonging the PT ... to identify the cause ... #prolonged #diagnosis ... #hematology #evaluation
Von Willebrand Disease - Most common inherited bleeding disorder Clinical • Easy bruising •
common inherited bleeding ... 2B) • Normal PT ... INR • Normal aPTT ... VonWillebrand #Disease #Diagnosis ... #Hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
- Differential Diagnosis ... - History of bleeding ... : INR/PT, aPTT(liver ... bypass), LFT (liver ... #hematology
Differential Diagnosis for a Prolonged PT and aPTT If the PT and the aPTT are both prolonged,
Differential Diagnosis ... PT and the aPTT ... • Reduced liver ... #Causes #diagnosis ... #differential #hematology
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
PT and/or aPTT ... Early liver disease ... Reduced liver synthesis ... #Causes #diagnosis ... #differential #hematology
Prothrombin Time (PT) and Partial Thromboplastin Time (PTT) Prothrombin Time (PT) - Often Elevated in: • Vitamin
Prothrombin Time (PT ... Prothrombin Time (PT ... inhibitor • Liver ... Thromboplastin #laboratory #hematology ... #diagnosis
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
• Prolonged PT ... Fibrinogen: ↓ • PT ... DIC • Severe Liver ... #Coagulation #diagnosis ... #management #hematology
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
- Differential Diagnosis ... liver failure, ... discern these causes ... #Differential #Diagnosis ... #Hematology
Hemophilia - Diagnosis and Management Diagnosis: • Consistent bleeding history (unless screening for disease in family members
established disease) • aPTT ... mixing study (aPTT ... normal in mild cases ... ) • PT/INR & von ... Management #treatment #hematology
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