14 results
Hydroxychloroquine Serum Measurement in SLE
 • Terminal elimination half-life = 40 days ([HCQI reflects long-term intake)
Measurement in SLE ... half-life = 40 days ([HCQI ... #Measurement #SLE ... #rheumatology # ... pharmacology #levels #lupus
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
- History of bleeding ... epistaxis, gingival bleeding ... test, ANA (e.g., SLE ... or if a primary hematologic ... #Workup #hematology
Top 10 situations when to think about lupus
1) Inflammatory joint pain (especially in the wrists and
Inflammatory joint pain ... and fingers, or pain ... 3) Limb oedema leading ... #diagnosis #sle ... erythematosus #rheumatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE ... autoantibodies that will cause ... inflammation, leading ... Erythematosus #SLE ... CNS #neurology #rheumatology
Aortitis - Differential Diagnosis Framework
Non-Infectious Aortitis:
 • Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
Polyarteritis Nodosa (PAN ... (RA), Systemic lupus ... erythematosus (SLE ... (SPA) • Other Causes ... Differential #Diagnosis #rheumatology
Hydroxychloroquine - Risks and Benefits in Lupus
Benefits:
↓ Disease activity, ↓ Flare, ↓ Damage, ↓ Corticosteroid dose,
and Benefits in Lupus ... other medications leading ... Hydroxychloroquine #hcq ... Risks #Benefits #Lupus ... #sideeffects #rheumatology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
• Fever is the main ... purpura to mucosal bleeding ... erythematosus [SLE ... Diagnosis #Management #Hematology ... #Rheumatology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
infections, bone pain ... -> AML: Blast crises ... Headaches, bone pain ... , fever, joint pain ... #Leukemia #Hematology
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
immune system, leading ... • They can cause ... Cryoglobulins Cause ... (e.g. systemic lupus ... classification #rheumatology
Polycythemia - Differential Diagnosis Algorithm
Polycythemia itself isn’t a diagnosis. Like many things, it is a condition
an underlying cause ... : neuro, heme (bleeding ... Better call hematology ... some time, let’s see ... Algorithm #workup #hematology