29 results
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm
Thrombocytopenia - Quantitative Defect
 • Decreased Production
 •
Causes of Bleeding ... Sequestration Disordered ... Connective Tissue Disorders ... #Bleeding #Bruising ... Algorithm #Causes #Hematology
Causes of Prolonged PT (INR), Prolonged PTT
 • Prolonged PT (INR), Prolonged PTT
 • Prolonged PT
Normal PT (INR) - Bleeding ... PT (INR) - No Bleeding ... Algorithm #Causes #Hematology ... #coagulation #disorders
Disorders of the Hepatic and Mesenteric Circulation

Platelets in Cirrhosis
Hypercoagulability in Cirrhosis
Bleeding in Cirrhosis
Portal Vein Thrombosis (PVT)
Mesenteric
Disorders of the ... in Cirrhosis Bleeding ... #Circulation #Disorders ... #Hepatology #Gastroenterology
Hypereosinophilia and Hypereosinophilic Syndrome

 • Secondary Hypereosinophilic Syndrome
 • Clinically Relevant HES Variants
 • When to
Hypereosinophilic Syndrome • Clinically ... suspect underlying hematologic ... disorders • Diagnosis ... and Treatment Algorithm ... Syndrome #HES #Hematology
Von Willebrand Disease - Most common inherited bleeding disorder 
Clinical 
 • Easy bruising 
 •
common inherited bleeding ... disorder Clinical ... • Prolonged bleeding ... factor VIII) Treatment ... Disease #Diagnosis #Hematology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
Intravascular Coagulation ... organ damage Clinical ... Treatment: ... diagnosis #causes #treatment ... #management #hematology
Managing warfarin INR

Warfarin dosage must be individualized according to the patient's response to the drug, and
lead to severe bleeding ... hemorrhage, while under-coagulation ... #pharmacology #treatment ... decisionaid #cardiology #hematology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Failure (ACLF) Clinical ... months without treatment ... Kidney Failure Coagulation ... Failure #Cirrhosis #Hepatology ... #gastroenterology
Bleeding risk calculators - HAS-BLED (atrial fibrillation) and IMPROVE (VTE prophylaxis for inpatients)
Important notes:
 • No
Bleeding risk calculators ... validated for VTE treatment ... studies suggest net clinical ... with very high bleeding ... Anticoagulation #Factors #Hematology
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework

== Quantitative or Qualitative defect in
- Disorders of ... of a platelet disorder ... inhibitor of a coagulation ... intravascular coagulation ... Differential #Diagnosis #Hematology