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management smear oncology rouleaux anemia classification differential disease microscopy treatment types vonwillebrand activation algorithm anticoagulation aplastic bariatric blood bypass calculators
Rouleaux formation is common in IgM gammopathy and may be particularly striking Genevieve Crane, MD, PhD@evemariecrane #Rouleaux #formation
Rouleaux formation ... #Rouleaux #formation ... gammopathy #MGUS #Clinical ... #Pathology #Hematology
Plasma cell leukemia with extensive rouleaux formation. Aggressive disease & patients typically younger than other forms
extensive rouleaux formation ... leukemia #rouleaux #formation ... #Clinical #Smear ... #Hematology #Pathology
Idiopathic Thrombocytopenic Purpura Clinical: • Gingival • Menorrhagia • GI bleeding • Intracranial
Thrombocytopenic Purpura Clinical ... Menorrhagia • GI bleeding ... only for severe bleeding ... Thrombocytopenia #Diagnosis ... #Overview #Hematology
Bleeding risk calculators - HAS-BLED (atrial fibrillation) and IMPROVE (VTE prophylaxis for inpatients) Important notes: • No
Bleeding risk calculators ... studies suggest net clinical ... with very high bleeding ... Anticoagulation #Factors #Hematology ... #Diagnosis
Von Willebrand Disease - Most common inherited bleeding disorder Clinical • Easy bruising •
common inherited bleeding ... disorder Clinical ... • Prolonged bleeding ... VonWillebrand #Disease #Diagnosis ... #Hematology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE) Clinical ... Pathogenesis involves the formation ... inflammation, leading ... permeability Diagnosis ... CNS #neurology #rheumatology
Indications for Serum Protein Electrophoresis (SPEP) • Suspected multiple myeloma, Waldenström's macroglobulinemia, primary amyloidosis, or related
pain, abnormal bleeding ... ) • Rouleaux formations ... • Unexplained pathologic ... Electrophoresis #SPEP #Hematology ... #Diagnosis
Autoagglutination should also be distinguished from “Rouleaux formation” wherein normal blood tends to form stacks on
from “Rouleaux formation ... #Clinical #Pathology ... Microscopy #Rouleaux #Formation ... #Hematology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Findings: • Bleeding ... organ damage Clinical ... significant fibrin clot formation ... #Coagulation #diagnosis ... treatment #management #hematology
Peripheral blood findings in microangiopathic hemolytic anemia. DIC is a clinical and laboratory diagnosis, not
DIC is a clinical ... and laboratory diagnosis ... hemolytic #anemia #Hematology ... #Pathology #Smear
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