40 results
Von Willebrand Disease - Most common inherited bleeding disorder 
Clinical 
 • Easy bruising 
 •
Von Willebrand Disease ... common inherited bleeding ... disorder Clinical ... VonWillebrand #Disease ... #Diagnosis #Hematology
Bleeding risk calculators - HAS-BLED (atrial fibrillation) and IMPROVE (VTE prophylaxis for inpatients)
Important notes:
 • No
Bleeding risk calculators ... studies suggest net clinical ... with very high bleeding ... #Risk #Scores # ... Anticoagulation #Factors #Hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
- History of bleeding ... PT, aPTT(liver disease ... K), H. pylori test ... thyroid function test ... Causes #Workup #hematology
Cold Urticaria
Prevalence - 0.05% in the population
Disease onset - Mostly 2nd to 4th decades of life
Causes
life Causes and clinical ... vertigo Diagnostic tests ... - Ice cube test ... , TempTest test ... Urticaria #diagnosis #rheumatology
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Initial screening test ... with more severe disease ... Used to monitor disease ... Hydroxychloroquine *Short ... Summary #diagnosis #rheumatology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Fever is the main clinical ... purpura to mucosal bleeding ... Liver function tests ... Diagnosis #Management #Hematology ... #Rheumatology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
Clinical features ... Noncontiguous spread • Clinical ... Hepatosplenomegaly, cytopenias(bleeding ... Lymphomas • Other hematologic ... #differential #hematology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of
Rheumatology Workup ... Studies in Rheumatic Diseases ... ANA and RF (if clinical ... #Rheumatic #Disease ... diagnosis #testing #Rheumatology
CHA2DS2VASc vs HAS-BLED scores for stroke risk and bleed risk on anticoagulation

C	Congestive Heart Failure	1

H	Hypertension	1

A2	Age >75	2

D	Diabetes Mellitus	1

S2	Stroke,
CHA2DS2VASc vs HAS-BLED scores ... 2 V Vascular disease ... S Stroke 1 B Bleeding ... AFib #Diagnosis #Hematology
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework

== Quantitative or Qualitative defect in
Von Willebrand’s disease ... cascade is intact - test ... Von Willebrand disease ... liver function tests ... Differential #Diagnosis #Hematology