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differential hepatology causes injury anemia classification dili hyperbilirubinemia management approach bariatric bruising bypass chemistry complications congenital conjugated dermatology direct drug
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm Thrombocytopenia - Quantitative Defect • Decreased Production •
Causes of Bleeding ... - Differential Diagnosis ... Algorithm Thrombocytopenia ... Iatrogenic) • Liver ... #Hematology
Inherited Non-hemolytic Disorders of Hyperbilirubinemia == Disorders of Conjugation == Gilbert Syndrome: • 5-10% of the population
Non-hemolytic Disorders ... of hemolysis or liver ... • Disorder is ... #hepatology #diagnosis ... #gastroenterology
Approach to Conjugated Hyperbilirubinemia - Differential Diagnosis Algorithm 1. Definition: T.bili elevation + >20% conjugated 2. Obtain RUQ
Algorithm 1. ... MRCP, ERCP, liver ... Hyperbilirubinemia #direct #bilirubin ... #Algorithm #gastroenterology ... #hepatology
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
- Differential Diagnosis ... Algorithm Low ... 80-100 fL) • Bleeding ... Renal Disease, Liver ... #Hematology
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
- Differential Diagnosis ... Algorithm Blood ... RBCs on Smear • Chronic ... Increased Unconjugated Bilirubin ... #Hematology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
- Differential Diagnosis ... Algorithm Vascular ... > 2 • NASH, Chronic ... RBC (hemolysis, bleeding ... #algorithm #hepatology
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI) DILI Types: • Intrinsic - predictable, dose dependent
Diagnosis and Management ... presentation • Chronic ... #differential #Diagnosis ... #algorithm #gastroenterology ... #hepatology
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
> 2 • NASH, Chronic ... injury: > 3 • Chronic ... RBC (hemolysis, bleeding ... #chemistry #diagnosis ... #differential #Hepatology
Causes of Fatigue - Differential Diagnosis Algorithm Endocrine • Hypo/Hyperthyroidism • Diabetes • Pituitary Insufficiency • Adrenal
- Differential Diagnosis ... Algorithm Endocrine ... Renal Failure • Liver ... Neoplastic / Hematologic ... • Somatization Disorder
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
DILI) - Stepwise Diagnosis ... Algorithm DILI ... Hepatic vascular disorder ... #Injury #Diagnosis ... #Algorithm #hepatology
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