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differential management algorithm anemia leukemia liver lymphocytic mds myelodysplastic treatment workup aclf acute calculation causes cholangitis cirrhosis comparison diffuse failure
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Chronic leukemia ... with a relatively chronic ... (Chronic Myeloid ... #Leukemia #Hematology ... #Oncology #Diagnosis
Aplastic Anemia - Illness Script Signs and symptoms: • Recurrent infections from neutropenia • Mucosal bleeding from
Aplastic Anemia ... neutropenia • Mucosal bleeding ... Consider stem cell ... #Anemia #diagnosis ... management #treatment #hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... Diagnosis: • ... aplasia • ITP ... #workup #oncology ... #hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Syndrome (MD) - Diagnosis ... dys- (abnormal) -plastic ... Allogeneic stem cell ... Management #treatment #hematology ... #oncology
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
- Differential Diagnosis ... Leukemia - History of Bleeding ... Age > 50 • Chronic ... Algorithm #Causes #Hematology ... #Oncology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia ... • Aplastic anemia ... ecchymoses, mucosal bleeding ... #Anemia #oncology ... #hematology #diagnosis
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... in those with CLD ... Failure #Cirrhosis #Hepatology ... #gastroenterology ... #management #diagnosis
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
Hepatosplenomegaly, cytopenias(bleeding ... Differential Diagnosis ... NonHodgkins #comparison #oncology ... #diagnosis #differential ... #hematology
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor The maturation factor is
• Anemia of chronic ... marrow failure: Aplastic ... defects (e.g. sickle cell ... Production #Index #hematology ... #differential #diagnosis
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Chronic Lymphocytic ... minimal tumor burden Diagnosis ... uw_IMresidency #CLL ... #Leukemia #oncology ... #hematology #hemeonc
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