18 results
Hypersegmented neutrophil in a case of acute myeloid leukemia.

Dysplastic neutrophils are typically hypolobated but can be
acute myeloid leukemia ... neutrophils #AML #Clinical ... #Hematology #Pathology ... #Smear
Plasma cell leukemia with extensive rouleaux formation. Aggressive disease & patients typically younger than other forms
Plasma cell leukemia ... primary plasma cell leukemia ... #PlasmaCell #leukemia ... rouleaux #formation #Clinical ... #Smear #Hematology
Approach to Leukocytosis - Differential Diagnosis Algorithm

Features of hematologic malignancy:
 • Symptoms: B-symptoms, bruising/bleeding, fatigue/weakness, immunosuppression
Differential Diagnosis Algorithm ... Features of hematologic ... B-symptoms, bruising/bleeding ... #hematology #WBC ... #Leukemoid
Acute promyelocytic leukemia (blood). Typical morphologic features are bilobed ("butterfly") nuclei with dispersed chromatin, subtle to
promyelocytic leukemia ... promyelocytic #leukemia ... APML #Pathology #Hematology ... #Clinical #Smear
Peripheral Blood Smear Analysis
Hypochromia
Megaloblastic Anemia
Schistocytes: Microangiopathic hemolytic anemia (e.g. DIC, TTP, HUS)
Microspherocytes: Autoimmune hemolytic anemia
Sickled red
Peripheral Blood Smear ... DIC, TTP, HUS) ... Peripheral #Blood #Smear ... #Analysis #hematology ... interpretation #clinical
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
peripheral blood smear ... Symptoms: • Malaise, bleeding ... • Peripheral smear ... Fibrinolysis & DIC ... #Hematology #Oncology
Causes of Thrombocytopenia - Differential Diagnosis Algorithm
 
Decreased Megakaryopoiesis
 • Aplastic Anemia
 • Toxic Damage (e.g.
Differential Diagnosis Algorithm ... Leukemia, Tumour ... • TTP/HUS • DIC ... Differential #Diagnosis #Algorithm ... #Causes #Hematology
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm
Reactive:
 - Systemic Inflammatory
     •
Differential Diagnosis Algorithm ... - History of Bleeding ... Lymphoblastic Leukemia ... Differential #Diagnosis #Algorithm ... #Causes #Hematology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
Intravascular Coagulation (DIC ... promyelocytic leukemia ... organ damage Clinical ... • Peripheral smear ... treatment #management #hematology
Peripheral blood findings in microangiopathic hemolytic anemia.  DIC is a clinical and laboratory diagnosis, not
DIC is a clinical ... arrow) Peripheral smear ... hemolytic #anemia #Hematology ... #Pathology #Smear