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management oncology algorithm anemia causes differential disease hodgkins lymphoma types vonwillebrand activation anticoagulation aplastic calculators cancer coagulation comparison cryofibrinogenemia cryoglobulinemia
Idiopathic Thrombocytopenic Purpura Clinical: • Gingival • Menorrhagia • GI bleeding • Intracranial
Thrombocytopenic Purpura Clinical ... Menorrhagia • GI bleeding ... only for severe bleeding ... Thrombocytopenia #Diagnosis ... #Overview #Hematology
Von Willebrand Disease - Most common inherited bleeding disorder Clinical • Easy bruising •
common inherited bleeding ... disorder Clinical ... • Prolonged bleeding ... VonWillebrand #Disease #Diagnosis ... #Hematology
Bleeding risk calculators - HAS-BLED (atrial fibrillation) and IMPROVE (VTE prophylaxis for inpatients) Important notes: • No
Bleeding risk calculators ... studies suggest net clinical ... with very high bleeding ... Anticoagulation #Factors #Hematology ... #Diagnosis
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
- Differential Diagnosis ... 80-100 fL) • Bleeding ... #Anemia #MCV #Classification ... #Differential #Diagnosis ... Algorithm #Causes #Hematology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
Autoimmune diseases • Clinical ... translocation • Types: Classification ... Hepatosplenomegaly, cytopenias(bleeding ... Differential Diagnosis ... #differential #hematology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Findings: • Bleeding ... organ damage Clinical ... Findings: • Bleeding ... #Coagulation #diagnosis ... treatment #management #hematology
Von Willebrand Disease Classification Type 1 (Accounts for ~3/4 of cases): • Defect: Quantitative defect (i.e. not
Willebrand Disease Classification ... : Severe (Clinically ... VonWillebrand #Disease #Classification ... #Types #diagnosis ... #hematology
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
Paradoxical spontaneous bleeding ... Cryofibrinogenemia Clinical ... : • + Clinical ... #rheumatology # ... hematology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Fever is the main clinical ... purpura to mucosal bleeding ... Activation #Syndrome #Diagnosis ... #Management #Hematology ... #Rheumatology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
immune system, leading ... Syndrome: • Clinical ... Labs/Diagnosis: ... #types #classification ... #rheumatology #
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