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management disease anemia aplastic oncology syndrome acquired activation algorithm anticoagulation calculators cancer causes classification coagulation dic differential disseminated factors hasbled
Von Willebrand Disease - Most common inherited bleeding disorder Clinical • Easy bruising •
common inherited bleeding ... factor VIII) Treatment ... Desmopressin (DDAVP) #VonWillebrand ... #Disease #Diagnosis ... #Hematology
Von Willebrand Disease - Clinical Presentation, Diagnosis and Management - Dr. Eric Strong @DrEricStrong - Strong Medicine
Presentation, Diagnosis ... EricsMedicalLectures/ #VonWillebrand ... #Disease #Diagnosis ... #Management #hematology ... #treatment
Acquired von Willebrand Syndrome - Diagnosis and Management • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
Willebrand Syndrome - Diagnosis ... #Acquired #vonWillebrand ... #Syndrome #Diagnosis ... #Management #treatment ... #hematology #differential
Bleeding risk calculators - HAS-BLED (atrial fibrillation) and IMPROVE (VTE prophylaxis for inpatients) Important notes: • No
Bleeding risk calculators ... validated for VTE treatment ... with very high bleeding ... Anticoagulation #Factors #Hematology ... #Diagnosis
Aplastic Anemia - Illness Script Signs and symptoms: • Recurrent infections from neutropenia • Mucosal bleeding from
neutropenia • Mucosal bleeding ... Symptomatic anemia Diagnosis ... megaloblastic anemia Treatment ... #management #treatment ... #hematology
Hemophilia - Diagnosis and Management Diagnosis: • Consistent bleeding history (unless screening for disease in family members
Hemophilia - Diagnosis ... Classify severity Treatment ... by a hemophilia treatment ... #Management #treatment ... #hematology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Findings: • Bleeding ... Treatment: ... #Coagulation #diagnosis ... #causes #treatment ... #management #hematology
Von Willebrand Disease Classification Type 1 (Accounts for ~3/4 of cases): • Defect: Quantitative defect (i.e. not
(uncommon) • Bleeding ... recessive • Bleeding ... EricsMedicalLectures/ #VonWillebrand ... Classification #Types #diagnosis ... #hematology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
purpura to mucosal bleeding ... Treatment: • Corticosteroids ... Activation #Syndrome #Diagnosis ... #Management #Hematology ... #Rheumatology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
ecchymoses, mucosal bleeding ... aplastic anemia Treatment ... Anemia #oncology #hematology ... #diagnosis #management
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