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management differential oncology algorithm workup blood causes leukemia myelodysplastic pancytopenia product reactions syndrome activation anticoagulation atopic atopy calculators chronic classification
Aplastic Anemia - Illness Script Signs and symptoms: • Recurrent infections from neutropenia • Mucosal bleeding from
Aplastic Anemia ... neutropenia • Mucosal bleeding ... Can progress to MDS ... #Anemia #diagnosis ... #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
myelodysplastic syndrome (MDS ... Hypocellular/Hypoplastic MDS ... abnormalities typical for MDS ... anemia Treatment ... #hematology #diagnosis
Bleeding risk calculators - HAS-BLED (atrial fibrillation) and IMPROVE (VTE prophylaxis for inpatients) Important notes: • No
- HAS-BLED (atrial ... ) and IMPROVE (VTE ... treatment, only ... Anticoagulation #Factors #Hematology ... #Diagnosis
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV Microcytic (MCV < 80) "TAILS": • Thalassemia
- Differential Diagnosis ... Non-hemolytic: ACD, Aplastic ... Reticulocytosis, MDS ... #Differential #Diagnosis ... #hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
dys- (abnormal) -plastic ... cytopenias (usually anemia ... only curative treatment ... Myelodysplastic #Syndrome #MDS ... #treatment #hematology
Pancytopenia - Workup and Differential Diagnosis Algorithm Consumption Disorders 1. Autoimmune Mediated Pancytopenia 2. Splenic Sequestration Peripheral Destruction
and Differential Diagnosis ... FISH • Acquired Aplastic ... Anemia • Hypoplastic ... MDS • Congenital ... #Algorithm #Hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
→ Refer to hematology ... hemolysis, deficiency anemia ... Rebound effect from treatment ... Malignancy: Metastatic cancer ... #Algorithm #hematology
Pancytopenia - Workup and Differential Diagnosis Algorithm Consumption Disorders 1. Autoimmune Mediated Pancytopenia 2. Splenic Sequestration Peripheral Destruction
and Differential Diagnosis ... FISH • Acquired Aplastic ... Anemia • Hypoplastic ... MDS • Congenital ... #Algorithm #Hematology
Hemophilia - Diagnosis and Management Diagnosis: • Consistent bleeding history (unless screening for disease in family members
mixing study (aPTT may ... center. ... Avoid meds that ... #Management #treatment ... #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Myelodysplastic Syndromes (MDS ... platelets) • MDS ... precursors MDS ... • Aplastic Anemia ... #hematology #oncology
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