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oncology management differential leukemia lymphocytic mds myelodysplastic algorithm calculation cancer causes hemeonc index infections infectiousdiseases mycobacteria myelodysplasia neutropenia nontuberculous ntm
Aplastic Anemia - Illness Script Signs and symptoms: • Recurrent infections from neutropenia • Mucosal bleeding from
Aplastic Anemia ... neutropenia • Mucosal bleeding ... stem cell transplant ... #Anemia #diagnosis ... #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Chronic leukemia ... (Chronic Myeloid ... - infiltrates (anemia ... #Leukemia #Hematology ... #Oncology #Diagnosis
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
dys- (abnormal) -plastic ... cytopenias (usually anemia ... Allogeneic stem cell ... #Management #treatment ... #hematology #oncology
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor The maturation factor is
deficiencies: Chronic ... marrow failure: Aplastic ... defects (e.g. sickle cell ... Production #Index #hematology ... #diagnosis #calculation
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia ... • Aplastic anemia ... ecchymoses, mucosal bleeding ... anemia Treatment ... #hematology #diagnosis
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... • Neutropenia, anemia ... aplasia • ITP ... microglobulin Treatment ... workup #oncology #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Chronic Lymphocytic ... minimal tumor burden Diagnosis ... 5) Symptoms of anemia ... Leukemia #oncology #hematology ... #hemeonc #diagnosis
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
are caused by bleeding ... • Aplastic Anemia ... Marrow Failure • Chronic ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
Causes of Neutropenia - Differential Diagnosis Neonate: - Infection - by far the most common cause -
- Differential Diagnosis ... hypertension and/or drug treatment ... Megaloblastic anemia-rare ... aplasia DOI: 10.1111 ... #causes #hematology
Nontuberculous Mycobacteria (NTM) Infections Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
Immunocompromised status • Chronic ... encounters due to NTM: Chronic ... other RGM • Plastic ... Hematologic malignancy ... Bone Marrow - Anemia
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