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diagnosis management oncology algorithm anticoagulation aplastic cancer causes chronic cll differential lymphocytic mds myelodysplastic syndrome thromboembolism venous activation calculators coagulation
Venous Thromboembolism Treatment Algorithm Branch points: Active bleeding? Active malignancy? Provoked? - Dr. Joseph Shatzel @Clotmaster #Management #VTE #DVT
Thromboembolism Treatment ... points: Active bleeding ... #Management #VTE ... Thromboembolism #Treatment ... #Hematology #Anticoagulation
Aplastic Anemia - Illness Script Signs and symptoms: • Recurrent infections from neutropenia • Mucosal bleeding from
neutropenia • Mucosal bleeding ... Treatment: • Consider ... to MDS or acute leukemia ... diagnosis #management #treatment ... #hematology
Bleeding risk calculators - HAS-BLED (atrial fibrillation) and IMPROVE (VTE prophylaxis for inpatients) Important notes: • No
Bleeding risk calculators ... ) and IMPROVE (VTE ... validated for VTE ... treatment, only ... Anticoagulation #Factors #Hematology
Approach to Leukocytosis - Differential Diagnosis Algorithm Features of hematologic malignancy: • Symptoms: B-symptoms, bruising/bleeding, fatigue/weakness, immunosuppression
Features of hematologic ... B-symptoms, bruising/bleeding ... hepatomegaly • Labs: anemia ... Diagnosis #Algorithm #hematology ... #WBC #Leukemoid
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Chronic Myelogenous Leukemia ... Non malignant hematologic ... effect following treatment ... Iron deficiency anemia ... Algorithm #Causes #Hematology
Treatment algorithm for VTE in Malignancy (A) Suggested treatment algorithm for symptomatic and incidental DVT or PE
for VTE in Malignancy ... at high risk of bleeding ... risk of recurrent VTE ... #DOAC #VTE #Malignancy ... Anticoagulation #Management #Hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Symptoms: • Malaise, bleeding ... fever, joint pain, bleeding ... night sweats, bleeding ... - infiltrates (anemia ... #Hematology #Oncology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
cytopenias (usually anemia ... transformation to acute leukemia ... only curative treatment ... Diagnosis #Management #treatment ... #hematology #oncology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Chronic Lymphocytic Leukemia ... • Most common leukemia ... 5) Symptoms of anemia ... marrow failure with anemia ... #oncology #hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Chronic Lymphocytic Leukemia ... • Most common leukemia ... • Neutropenia, anemia ... microglobulin Treatment ... workup #oncology #hematology
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