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diagnosis differential oncology algorithm aplastic blood causes nutrition product reactions treatment activation atlas b12 classification coagulation dic disseminated factor7 factoreight
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
80 fL) • Iron Deficiency ... 80-100 fL) • Bleeding ... 100 fL) • B12 Deficiency ... • Folate Deficiency ... Algorithm #Causes #Hematology
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Microcytic - Iron-deficiency ... Thalassemia, Iron-deficiency ... Liver diseases, Bleeding ... cells - G-6-PD deficiency ... #differential #hematology
Aplastic Anemia - Illness Script Signs and symptoms: • Recurrent infections from neutropenia • Mucosal bleeding from
Aplastic Anemia ... neutropenia • Mucosal bleeding ... • Symptomatic anemia ... #diagnosis #management ... #treatment #hematology
Etiologies of Folate Deficiency • Decreased dietary intake - uncommon in this era • Increased requirements
Etiologies of Folate Deficiency ... have hemolytic anemia ... develop folate deficiency ... interfered with leading ... differential #diagnosis #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
ecchymoses, mucosal bleeding ... , GATA2 deficiency ... , CTLA4 deficiency ... #oncology #hematology ... #diagnosis #management
Algorithm for managing FVII deficiency. *Mild bleeding history includes minor epistaxis, menorrhagia, gastrointestinal bleeding, joint and soft
managing FVII deficiency ... *Mild bleeding history ... #FVII #deficiency ... Factor7 #Algorithm #management ... #Hematology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Findings: • Bleeding ... Findings: • Bleeding ... thrombopoietin deficiency ... causes #treatment #management ... #hematology
Hemophilia A Prophylaxis (Factor Eight Deficiency) Who Needs Prophylaxis? Primary Prophylaxis: • Severe deficiency (activity level <1%) even
(Factor Eight Deficiency ... without hx of bleeding ... Prophylaxis: • 2 bleeding ... #FactorEight #Deficiency ... #hematology #management
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Symptoms: • Malaise, bleeding ... fever, joint pain, bleeding ... , weight loss, abdominal ... - infiltrates (anemia ... #Leukemia #Hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
unusual bruising or bleeding ... are caused by bleeding ... or folic acid deficiency ... treatments • Copper deficiency ... Syndromes #diagnosis #hematology
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