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diagnosis differential lymphadenopathy anemia diffuse focal localized management anticoagulation aplastic ascites cancer classification doac emergencies hemeonc malignancy malignant mcv mds
Causes of Diffuse and Localized Lymphadenopathy - Differential Diagnosis Algorithm • Reactive (Inflammatory / Infectious) •
Causes of Diffuse ... • Neoplastic (Leukemia ... Lymphadenopathy #LAD ... #Causes #Hematology ... #Oncology
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
Causes of Diffuse ... - History of Bleeding ... Lymphadenopathy #LAD ... #Causes #Hematology ... #Oncology
Causes of Localized Lymphadenopathy - Differential Diagnosis Algorithm Cervical: - Anterior • Infection
Causes of Localized ... Esophagus) • Abdominal ... Lymphadenopathy #LAD ... #Causes #Hematology ... #Oncology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
activity • ↓ LAP ... -> AML: Blast crises ... fever, joint pain, bleeding ... , weight loss, abdominal ... #Hematology #Oncology
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Causes of Anemia ... Differential Diagnosis Algorithm ... Thalassemia • Lead ... 80-100 fL) • Bleeding ... #Causes #Hematology
Treatment algorithm for VTE in Malignancy (A) Suggested treatment algorithm for symptomatic and incidental DVT or PE
at high risk of bleeding ... initiated after a LMWH lead-in ... interactions and bleeding ... Anticoagulation #Management #Hematology ... #Oncology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
ecchymoses, mucosal bleeding ... and petechiae Causes ... virus (EBV) • Leukemia ... Aplastic #Anemia #oncology ... #hematology #diagnosis
Polycythemia - Differential Diagnosis Algorithm Polycythemia itself isn’t a diagnosis. Like many things, it is a condition
Differential Diagnosis Algorithm ... : neuro, heme (bleeding ... Better call hematology ... about secondary causes ... #workup #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Chronic Myelogenous Leukemia ... • Hairy Cell Leukemia ... compounds, alcohol, lead ... Syndromes #diagnosis #hematology ... #oncology
Summary of Oncologic Emergencies Neutropenic fever: - Fever + ANC < 500 → start cefepime ± vancomycin (if
CT abdomen if abdominal ... syndrome): - Hematologic ... Simultaneous clotting and bleeding ... Treat underlying cause ... Usually myeloid leukemias
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