33 results
diagnosis differential algorithm oncology management classification workup hemolytic leukemia extravascular hemolysis intravascular lymphocytic mds myelodysplastic secondary thrombocytosis abg acid acidbase
Blood Disorders - Markers and Differential Diagnosis Algorithm Acute • Myloid (AML) - CD13, CD33, CD34,
Blood Disorders ... - CD7, CD3 Chronic ... • Myloid Disorders ... Pelger-Huet, Macrocytic anemia ... #hematology #Markers
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Chronic leukemia ... (Chronic Myeloid ... -> AML: Blast crises ... - infiltrates (anemia ... #Leukemia #Hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
- History of bleeding ... practices that could ... changes), high MCV anemia ... not required in all ... #Workup #hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Causes of Thrombocytosis ... : • Acute or Chronic ... • Rheumatic disorders ... Iron deficiency anemia ... #Hematology
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
, Chronic disease ... Unstable hemoglobin disorders ... Agglutinate: Cold ... , Paroxysmal cold ... differential #diagnosis #hematology
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Causes of Anemia ... of Chronic Disease ... 80-100 fL) • Bleeding ... Diagnosis #Algorithm #Causes ... #Hematology
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
Causes of Thrombocytosis ... malignancies • Anemia ... inflammatory disorders ... myeloid leukemia (CML ... #hematology #secondary
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... ) (e.g. lupus, CLL ... lymphoproliferative disorders ... differential #diagnosis #hematology ... #anemia
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
RBCs on Smear • Chronic ... • Anemia of Chronic ... • RBC Membrane Disorder ... Diagnosis #Algorithm #Causes ... #Hematology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
lymphoproliferative disorder ... lymphoid malignancy (CLL ... • Symptoms of anemia ... • hemolytic anemia ... #hematology #diagnosis
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