18 results
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
the peripheral blood ... Blast cells - Blood ... -> AML: Blast crises ... - infiltrates (anemia ... #Hematology #Oncology
Blood Disorders - Markers and Differential Diagnosis Algorithm 
Acute
 • Myloid (AML) - CD13, CD33, CD34,
Blood Disorders ... Pelger-Huet, Macrocytic anemia ... • Lymphoid (CLL ... - Amy Chung, MD ... #Disorders #hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
- History of bleeding ... plateletcount), peripheral blood ... changes), high MCV anemia ... not required in all ... #Workup #hematology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
lymphoproliferative disorders ... Lymphocytosis: Absolute blood ... • Neutropenia, anemia ... leukemia #CLL ... workup #oncology #hematology
Aplastic Anemia - Illness Script
Signs and symptoms:
 • Recurrent infections from neutropenia
 • Mucosal bleeding from
neutropenia • Mucosal bleeding ... Consider stem cell ... Can progress to MDS ... or acute leukemia ... management #treatment #hematology
Causes of Thrombocytosis - Differential Diagnosis
Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis):
 • Acute infection
 • Solid organ
malignancies • Anemia ... Chronic inflammatory disorders ... Chronic myeloid leukemia ... (CML) - Dr. ... #hematology #secondary
Acute promyelocytic leukemia (blood). Typical morphologic features are bilobed ("butterfly") nuclei with dispersed chromatin, subtle to
(blood). ... I see all of these ... features in most cases ... Kyle Bradley, MD ... APML #Pathology #Hematology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
are a group of disorders ... caused by blood ... cell count (anemia ... by bleeding (petechiae ... Syndromes #diagnosis #hematology
Basophilia - Differential Diagnosis Framework

Basophils < 1% of the total white blood cell count
Basophils function similarly
the total white blood ... Myeloproliferative Disorders ... Chickenpox Other Causes ... Differential #Diagnosis #causes ... #hematology #basophils
Red Blood Cell (RBC) Morphology
Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Red Blood Cell ( ... Liver Disease, MDS ... disease, McLeod blood ... Unstable hemoglobin disorders ... differential #diagnosis #hematology