27 results
Causes of Prolonged PT (INR), Prolonged PTT
 • Prolonged PT (INR), Prolonged PTT
 • Prolonged PT
Causes of Prolonged ... Normal PT (INR) - Bleeding ... PT (INR) - No Bleeding ... #Hematology #coagulation ... #disorders
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
- History of bleeding ... epistaxis, gingival bleeding ... plateletcount), peripheral blood ... or if a primary hematologic ... #Workup #hematology
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm
Thrombocytopenia - Quantitative Defect
 • Decreased Production
 •
Causes of Bleeding ... Sequestration Disordered ... Connective Tissue Disorders ... Coagulation #Bleeding ... #Hematology
Basophilia - Differential Diagnosis Framework

Basophils < 1% of the total white blood cell count
Basophils function similarly
the total white blood ... during an allergic reaction ... Myeloproliferative Disorders ... Or Inflammatory Reactions ... #hematology #basophils
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Eosinophil Disorders ... • Peripheral blood ... for secondary causes ... allergy, drug reaction ... Differential #diagnosis #hematology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
, or other causes ... fever • Drug reactions ... Differential #Diagnosis #hematology ... #rheumatology # ... #nonpalpable #dermatology
Causes of Neutropenia - Differential Diagnosis
Neonate:
 - Infection - by far the most common cause
 -
Causes of Neutropenia ... Idiosyncratic drug reactions ... Idiosyncratic drug reactions-most ... including white blood ... #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... Other: Transfusion reaction ... lymphoproliferative disorders ... Extravascular #Causes ... differential #diagnosis #hematology
Tranexamic Acid - Indications and Pharmacology
Pharmacokinetics:
 • MOA: Inhibits plasminogen activation to plasmin & inhibits fibrinolysis
: Urine Common Uses ... Hemoptysis, GI Bleeding ... rapid injection; Nausea ... vomiting, diarrhea & abdominal ... #Pharmacology #hematology
Overall Approach to Anemia - Differential Diagnosis Algorithm

Blood Loss
 • Acute Bleed - Normocytic / Normochromic
Diagnosis Algorithm Blood ... • RBC Membrane Disorder ... RBC Metabolism Disorder ... Diagnosis #Algorithm #Causes ... #Hematology