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review differential management medications cardiology agonists algorithm amikacin aminoglycosides antagonists antifungal antimuscarinic antipsychotics bloodstream catheter causes checklist crbsi criticalcare dalfopristin
Daptomycin - Antibiotics Class Overview Mechanism: Lipopeptide antibiotic – forms transmembrane channels and depolarizes cells.
Daptomycin - Antibiotics ... Class Overview ... MRSA bacteremia/endocarditis ... cidal nature) #Pharmacology ... #Overview #Daptomycin
Synercid (Quinupristin/Dalfopristin) (IV) - Antibiotics Class Overview Mechanism: “Streptogramins”– inhibits sequential steps in ribosomal synthesis Spectrum: covers MRSA
Dalfopristin) (IV) - Antibiotics ... Class Overview ... for bacteremia/endocarditis ... #Pharmacology #Antibiotics ... #Review #Overview
Aminoglycosides - Antibiotics Class Overview Gentamicin, Tobramycin, Amikacin, Streptomycin -30S inhibitor (all IV) Spectrum: Extremely efficacious vs.
Aminoglycosides - Antibiotics ... Class Overview ... effect (mainly in endocarditis ... #Pharmacology #Antibiotics ... #Review #Overview
Flutycosine - Antibiotics Class Overview - Mechanism: 5-FC interferes with DNA and protein synthesis. Only
Flutycosine - Antibiotics ... Class Overview ... candidal infections (endocarditis ... #Pharmacology #Antibiotics ... #Review #Overview
Suspected catheter-related bloodstream infection - Management Algorithm • Temperature 37.8 C • Rigors
Antibiotic Management ... Hemodynamically stable ... metastatic infection (endocarditis ... Hernodynamically stable ... Algorithm #CRBSI #diagnosis
Endocarditis checklist Initial evaluation • Peripheral blood cultures (three sets at three different sites) • Additional culture
Endocarditis checklist ... suspect right-sided endocarditis ... course • Adjust antibiotics ... telemetry for heart block ... #criticalcare #diagnosis
Endocarditis Summary Who? Infectious: • Pre-existing valvular disease • Prosthetic valve • Congenital heart disease • IV substance use • IV catheter • Recent
Differential Diagnosis ... Diagnosis? ... • IV Antibiotics ... sided IE: heart block ... lesions, heart block
Common Medications Known to Prolong QTc Antiarrhythmics - Amiodarone, sotalol, flecainide, quinidine, dronedarone, dofetilide Vasopressors/inotropes - Epinephrine, norepinephrine,
, venlafaxine Antibiotics ... #differential #diagnosis ... #pharmacology # ... table
First Generation Anti-Psychotics: Mechanisms and Side Effects Typical/Conventional Anti-Psychotics - Examples: Haloperidol, Chlorpromazine ACh M1 antagonist - Block
M1 antagonist - Block ... H1 antagonist - Block ... arterioles -> less able ... #SideEffects #pharmacology ... #diagnosis #psychiatry
Endocarditis - Overview and Differential Diagnosis Framework Who? Infectious: • Pre-existing valvular disease • Prosthetic valve • Congenital heart disease • IV
Endocarditis - Overview ... and Differential Diagnosis ... Treatment • IV antibiotics ... sided IE: Heart block ... lesions, heart block
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