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differential management leukemia lymphocytic thrombocytosis aclf classification diffuse failure gap globulin hemeonc hodgkins laboratory lad liver lymphadenopathy lymphoma mds myelodysplasia
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Infectious: • Acute ... disorders • Celiac disease ... effect following treatment ... #Algorithm #Causes ... #Hematology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... Failure (ACLF) Clinical ... in those with CLD ... months without treatment ... #Hepatology #gastroenterology
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
• Rheumatoid Arthritis ... Fatigue • Acute ... Age > 50 • Chronic ... #Algorithm #Causes ... #Hematology #Oncology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
→ Refer to hematology ... for workup, including ... , Celiac disease ... • Infections: Chronic ... #Algorithm #hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... cells can indicate disease ... ’s lymphoma or acute ... #workup #oncology ... #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Leukemia (CLL) ... immunophenotype Clinical ... chemotherapy for low-risk disease ... #Leukemia #oncology ... #hematology #hemeonc
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Sweet Syndrome Acute ... with systemic disease ... Causes: - Idiopathic ... Treatment: - Systemic ... #dermatology #oncology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... Screening Tests for Acute ... Screening Tests for Chronic ... ANA and RF (if clinical ... #laboratory #workup
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Albumin > 4) Work-up ... (RA, Temporal arteritis ... : Cirrhosis, ETOH ... gastric tumors • Hematology ... #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... Marrow Failure • Chronic ... Myeloproliferative Disease ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
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