132 results
Blood Disorders - Markers and Differential Diagnosis Algorithm 
Acute
 • Myloid (AML) - CD13, CD33, CD34,
Differential Diagnosis Algorithm ... or λ), Smudge Cells ... - B-cell ... Amy Chung, MD, MSc ... Differential #Diagnosis #Algorithm
Causes of Hypokalemia - Differential Diagnosis Algorithm
Increased Loss 
 - Increased GI Loss
 - Increased Urinary
Differential Diagnosis Algorithm ... - Increased Cell ... imports K+ into cells ... Differential #Diagnosis #Algorithm ... potassium #low #pathophysiology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Differential Diagnosis Algorithm ... ~10% - B-Cell ... Amy Chung, MD, MSc ... Classification #pathophysiology ... #differential #algorithm
Inflammatory Cascade: Pathogenesis and Clinical Findings
Continued Innate Immunity
 • Phagocytosis: (main mechanism) neutrophils and macrophages engulf
Pathogenesis and Clinical ... Natural Killer Cells ... • Humoral: (B cell ... : (T cell response ... #Inflammation #pathophysiology
Type IV Hypersensitivity: Pathogenesis and clinical findings
Definition: Unique because it is entirely T-Cell mediated; exposure to
Pathogenesis and clinical ... is entirely T-Cell ... allergen-specific T-Cell ... harmful -> Th Cells ... Allergy #Immunology #pathophysiology
Hypercalcemia of Malignancy - Pathophysiology
PTH-mediated
 • Parathyroid cancer
 • Ectopic production: Small cell lung cancer, ovarian
of Malignancy - Pathophysiology ... production: Small cell ... of lung, Renal Cell ... Hypercalcemia #Malignancy #Pathophysiology ... Differential #Diagnosis #algorithm
Type II Hypersensitivity: Pathogenesis and clinical findings
Definition: When antigens bind to the body's cell surfaces, forming
Pathogenesis and clinical ... to the body's cell ... receptor on body cell ... -> B-Cells with ... Allergy #Immunology #pathophysiology
Acute Rheumatic Fever: Pathogenesis and Clinical Findings

Delayed autoimmune reaction
-> Molecular mimicry
-> GAS antigen cross-reacts with host
->
Pathogenesis and Clinical ... B and CD-4+ T cells ... CRP Neuronal cell ... surface targeted -> Cell ... RheumaticFever #pathophysiology
Retinoblastoma: Pathogenesis and clinical findings
 • Sporadic mutation -> One allele of RB1 tumor suppressor gene
Pathogenesis and clinical ... mutated in one cell ... transformation of the cell ... mutated in all cells ... Retinoblastoma #pathophysiology
Humoral Immunity - Pathogenesis and Clinical Findings
Antigens (Ag) are produced from pathogens (bacteria, viruses, fungi, parasites)
Pathogenesis and Clinical ... Ag-presenting cells ... CD4+ helper T cells ... or plasma cells ... Humoral #Immunity #pathophysiology