42 results
diagnosis signs management neurology syndrome vasculitis differential hematology complications endocrinology ophthalmology acute clinical oncology pathology rheumatology temporal urology acanthocyte agammaglobulinemia
Retinoblastoma: Pathogenesis and clinical findings • Sporadic mutation -> One allele of RB1 tumor suppressor gene
mutated in one cell ... mutated in all cells ... Retinoblastoma Signs / Symptoms ... Retinoblastoma #pathophysiology ... diagnosis #signs #symptoms
Features of a Sickle Cell Crisis Sickle-cell disease - an autosomal recessive blood disorder. Characterized by red
Features of a Sickle Cell ... Crisis Sickle-cell ... These cells can ... The underlying pathophysiology ... Features #Signs #Symptoms
Acute Rheumatic Fever: Pathogenesis and Clinical Findings Delayed autoimmune reaction -> Molecular mimicry -> GAS antigen cross-reacts with host ->
B and CD-4+ T cells ... CRP Neuronal cell ... surface targeted -> Cell ... RheumaticFever #pathophysiology ... diagnosis #signs #symptoms
Giant Cell (Temporal) Arteritis: Pathogenesis and investigations Risk Factors: - Unclear environmental triggers (may be viral, not
Giant Cell (Temporal ... old; F>M Signs/Symptoms ... Anemia - Giant cells ... Temporal #Arteritis #Pathophysiology ... Diagnosis #Signs #Symptoms
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Reed-Sternberg (RS) Cells ... (LP) tumour B cells ... pattern of spread, B symptoms ... ~10% - B-Cell ... Classification #pathophysiology
Stress Fracture: Pathogenesis and clinical findings Abnormal biomechanics, Repetitive impact activities => Repetitive subthreshold mechanical loading => Bone strain =>
to repair => Microscopic ... #orthopedics #pathophysiology ... #symptoms #signs
A red blood cell (red arrow) is seen crossing the basement membrane (blue arrow) and losing
A red blood cell ... pathology #clinical #pathophysiology ... #microscopy
X-Linked Agammaglobulinemia: Pathogenesis and clinical findings The epidemiology of this disease is 1/340,000 births and roughly double
involved in B cell ... from precursor cells ... -> Impaired B cell ... immunity Signs/Symptoms ... Agammaglobulinemia #XLinked #pathophysiology
Hashitoxicosis ‘Leakage’ symptoms of active Hashimoto’s disease - Hashitoxicosis (Htx) can occur during the initial hyperthyroid stage in
Hashitoxicosis ‘Leakage’ symptoms ... lymphocytes and plasma cells ... ‘Leakage’ symptoms ... due to thyroid cell ... Endocrinology #Diagnosis #Pathophysiology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
caused by blood cells ... age 70 years Symptoms ... abnormal under the microscope ... abnormal under a microscope ... abnormal under the microscope
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