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diagnosis differential hyperkalemia potassium rheumatology high neurology pharmacology algorithm comparison diuresis diuretics druginduced erythematosus excretion gravis hcq hydroxychloroquine k levels
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... and Management ... versus DIL • ... Positive in 60-80% of cases ... : Chronic disease
Causes of Seizures - Differential Diagnosis Algorithm Unprovoked - Epilepsy: • Focal: Simple, Complex • Generalized: Absence,
Causes of Seizures ... ICH, Cerebral venous ... Toxic: Alcohol, Medication ... Hyperglycemia, Hyponatremia ... #neurology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Discontinuation of causal ... versus DIL • ... : Chronic disease ... #table #rheumatology ... #diagnosis #management
Hydroxychloroquine Serum Measurement in SLE • Terminal elimination half-life = 40 days ([HCQI reflects long-term intake)
Measurement in SLE ... 200ng/mL Best indications ... Insufficient blood ... pharmacology #levels #lupus ... #management
Diuretics and Agents Regulating Renal Excretion Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide) • Glaucoma • Epilepsy • Altitude
irrigation • Management ... Kidney stones caused ... Excretion #Diuresis #Nephrology ... #Pharmacology #Medications ... #Table
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
deficiency • Renal insufficiency ... /Failure • SLE ... Medications 2. ... differential #diagnosis #causes ... potassium #high #nephrology
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
deficiency • Renal insufficiency ... /Failure • SLE ... Medications 2. ... differential #diagnosis #causes ... potassium #high #nephrology
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
rheumatoid arthritis, SLE ... Respiratory insufficiency ... inhibition - Chronic ... Gravis #diagnosis #management ... #neurology
Hyperkalemia - Diagnosis and Management - GrepMed Handbook S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Etiology: • Medications ... only if no clear cause ... and Elimination (see ... Table below) ... Treatment #potassium #nephrology
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