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algorithm erythematosus lupus systemic anemia causes workup autoantibodies deficiency dermatology disorders druginduced drugs g6pd hemolytic mimickers nonpalpable normocytic palpable platelet
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
→ Refer to hematology ... blood loss, Acute hemolysis ... Inflammatory Conditions: Rheumatologic ... • Reaction to Medications ... #hematology
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
Volume (MCV) - Differential ... Diagnosis Algorithm ... RA, SLE, PRV, Chronic ... Bleed • Hemolysis ... #Causes #Hematology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
- Differential ... Diagnosis Algorithm ... genotypes): SS, SC, SE ... #Anemia #Differential ... #workup #hematology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... Diagnosis Framework ... DIC/TTP/HUS - Hemolytic ... #Diagnosis #hematology ... #rheumatology #
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Lymphadenopathies 7% - Hemolytic ... involvement 3% SLE-Related ... (aPL) 30-45% Differential ... Lupusreference #SLE ... #rheumatology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Platelet Disorders - Differential ... Diagnosis and Workup ... family history - Medications ... test, ANA (e.g., SLE ... #Workup #hematology
Medications to Avoid in Patients with G6PD Deficiency Due to Risk of Hemolysis - Chloroquine (Aralen)*
Medications to Avoid ... Due to Risk of Hemolysis ... #Medications #Differential ... #Diagnosis #Pharmacology ... #Hematology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... Diagnosis: • ANCA-associated ... Non-autoimmune rheumatologic ... activation and/or medications ... #Rheumatology
Drug Induced Systemic Lupus Erythematosus > 100 drugs have been associated with drug-induced SLE High risk (>5%): •
with drug-induced SLE ... Erythematosus #medications ... #drugs #pharmacology ... #risk #differential ... #diagnosis #rheumatology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Vasculitis - Differential ... Diagnosis Framework ... diseases, such as SLE ... infiltrates/cavities, hemoptysis ... #Diagnosis #Rheumatology
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