1286 results
Complement Pathways
- Classical Pathway
- Lectin Pathway
- Alternative Pathway

#Complement #Pathway #hematology #pathophysiology
Complement Pathways ... Alternative Pathway #Complement ... #Pathway #hematology
Causes of Hemolytic Anemia - Differential Diagnosis
Inherited
 • Membrane
 • Internal
    - Hemoglobin
Antibody/DAT+ - Complement ... Diagnosis #Causes #hematology
Complement Deficiency Testing Algorithm
 • Normal CH50 and AH50 AND High suspicion for complement deficiency
 •
Complement Deficiency ... suspicion for complement ... ARUPConsult @ARUPLabs #Complement ... Testing #Algorithm #hematology
Warm vs Cold Autoimmune Hemolytic Anemia
Warm Autoimmune Hemolytic Anemia:
 • Mechanism: IgG and Complement-mediated
 • Etiology:
Mechanism: IgG and Complement-mediated ... Mechanism: IgM and Complement-mediated ... Hemolytic #Anemia #hematology
Thrombotic Microangiopathies - Primary Thrombotic Microangiopathy (TMA) - Differential Diagnosis Table

 • Thrombotic Thrombocytopenic Purpura (TTP)
HUS (aHUS) - Complement-mediated ... Microangiopathy #TMA #hematology
Differential diagnosis of schistocytes / fragmentation hemolysis:
 • Thrombotic microangiopathies (TMA)
    - TTP
(ST-HUS) - Complement-mediated ... differential #diagnosis #hematology
Causes of Hypocomplementemia - CHAMPS Mnemonic
C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis
H - Heavy Chain deposition
Hypocomplementemia #Low #Complement ... #differential #hematology
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm
Extravascular - Spleen and RES-mediated hemolysis
 -
perfringens - Complement-Mediated ... Algorithm #Causes #Hematology
Tranexamic Acid - Indications and Pharmacology
Pharmacokinetics:
 • MOA: Inhibits plasminogen activation to plasmin & inhibits fibrinolysis
fibrinolysis (reduces complement ... #Pharmacology #hematology
Our approach to the diagnosis and initial management of patients with suspected HIT. Our approach is
imprecise, and complemented ... Diagnosis #Management #Hematology