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diagnosis clinical rheumatology erythematosus ultrasound systemic cardiology classification comparison differential echocardiogram joint knee management constrictive cp criteria druginduced musculoskeletal pathophysiology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Drug Induced Lupus ... Lupus (DIL): ... 90% - Low complement ... 80% - Low complement ... management of SLE
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... (SLE) - Diagnosis ... , oral ulcers, Lupus ... 80% - Low complement ... #lupus #Systemic
SLICC SLE Diagnostic Criteria - Systemic Lupus Erythematosus Clinical and Immunologic Criteria CLINICAL CRITERIA - ACUTE CUTANEOUS LUPUS
SLICC SLE Diagnostic ... Criteria - Systemic Lupus ... ACUTE CUTANEOUS LUPUS ... anticoagulant - Low complement ... #Rheumatology #SLE
Systemic Lupus Erythematosus (SLE): Pathogenesis • Genetic factors (Mutations in HLA- DR2/HLA-DR3 genes, complement genes, cytokine
Systemic Lupus Erythematosus ... (SLE): Pathogenesis ... HLA-DR3 genes, complement ... #Systemic #Lupus ... Erythematosus #SLE
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
Systemic Lupus Erythematosus ... (SLE): Musculoskeletal ... #Systemic #Lupus ... Erythematosus #SLE ... #MSK #Musculoskeletal
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
Criteria for Systemic Lupus ... Acute cutaneous lupus ... anticoagulant • Complement ... Classification #Criteria #SLE ... #Systemic #Lupus
Lupus - Role of complement and anti-dsDNA for the detection of flares Complement - ↓ Decreased Anti-dsDNA -
Lupus - Role of ... complement and anti-dsDNA ... detection of flares Complement ... Increased #Lupus ... #SLE #flares #laboratory
Joint Disorders - Differential Diagnosis Algorithm Monoarthritis • Septic • Crystalline - Gout
Polyarthritis • Systemic Lupus ... with Systemic Lupus ... Erythematosus (SLE ... Amy Chung, MD, MSc ... Joint #Disorders #msk
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... anti-Smith Ab, low complements ... RNP antibodies, Complement ... : Drug induced SLE ... SSA can rule in SLE
Tricuspid Stenosis on RV Angiogram RA, RV angio shows domed less mobile TV suggestive of severe TS
isolated TS without MS ... Patient had SLE ... with Lupus nephritis
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