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differential management cardiology causes clinical algorithm rheumatology types pulmonary table hematology radiology lupus gastroenterology pocus nephrology peds neurology erythematosus workup
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
EULAR/ACR Classification ... anticoagulant • Complement ... #EULARACR #Classification ... #Criteria #SLE ... Erythematosus #diagnosis
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
anti-Smith Ab, low complements ... Skin Disease Classification ... Differential Diagnosis ... RNP antibodies, Complement ... Erythematosus #Diagnosis
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
diseases: - 10% SLE ... Labs/Diagnosis: ... • Low serum C4 complement ... erythematosus (SLE ... #types #classification
Effect of Selected Diseases on Complement Levels - C3, C4 • SLE C3 ↓ C4 ↓↓
Selected Diseases on Complement ... Levels - C3, C4 • SLE ... • Infection eg SBE ... ThePeanutKidney #Complement ... #differential #diagnosis
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
- Differential Diagnosis ... Differential Diagnosis ... against MPO • Complement ... vasculitis, and SLE ... #rheumatology #classification
Classifications for COPD through the Years Graphic Design by Mr. Ramon Thompson #Diagnosis #COPD #Classification #Severity #Critera #GOLD2006
Classifications ... Ramon Thompson #Diagnosis ... #COPD #Classification
Pulmonary Renal Syndromes and Mimics - Differential Diagnosis Framework Diffuse alveolar hemorrhage + rapidly progressive glomerulonephritis 90%: -
- Differential Diagnosis ... anti-GBM) 10%: - Low Complement ... Levels: SLE, Cryoglobulinemic ... Vasculitis - Normal Complement ... #Differential #Diagnosis
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Erythematosus (SLE ... ) - Diagnosis and ... are evocative of SLE ... 80% - Low complement ... Erythematosus #Diagnosis
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Induced Lupus vs SLE ... 90% - Low complement ... Erythematosus (SLE ... 80% - Low complement ... #rheumatology #diagnosis
Systemic Lupus Erythematosus (SLE): Pathogenesis • Genetic factors (Mutations in HLA- DR2/HLA-DR3 genes, complement genes, cytokine
Erythematosus (SLE ... HLA-DR3 genes, complement ... self-antigens, activating complement ... Erythematosus #SLE
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