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clinical pocus cardiology diagnosis a4c differential ultrasound embolism management plax acutepe rheumatology mcconnells s4c sign psax pulmonaryembolism radiology algorithm cardiac
Effect of Selected Diseases on Complement Levels - C3, C4 • SLE C3 ↓ C4 ↓↓
Selected Diseases on Complement ... Levels - C3, C4 • SLE ... • Infection eg SBE ... ThePeanutKidney #Complement
Pulmonary Renal Syndromes and Mimics - Differential Diagnosis Framework Diffuse alveolar hemorrhage + rapidly progressive glomerulonephritis 90%: -
Pulmonary Renal ... anti-GBM) 10%: - Low Complement ... Levels: SLE, Cryoglobulinemic ... Vasculitis - Normal Complement ... Kumfer @AnnKumfer #Pulmonary
Pulmonary Embolism on POCUS Echocardiogram Mid 30's female with chest pain/dyspnea. Triage EKG (no prior).
Pulmonary Embolism ... on POCUS Echocardiogram ... See thread for POCUS ... Pulmonary embolism ... Embolism #POCUS #Echocardiogram
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 Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Induced Lupus vs SLE ... 90% - Low complement ... 80% - Low complement ... management of SLE ... druginduced #lupus #sle
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Erythematosus (SLE ... are evocative of SLE ... 80% - Low complement ... management of SLE ... Lupusreference #SLE
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
staining): • Low Complement ... Idiopathic • Normal Complement ... With associated pulmonary
Systemic Lupus Erythematosus (SLE): Pathogenesis • Genetic factors (Mutations in HLA- DR2/HLA-DR3 genes, complement genes, cytokine
Erythematosus (SLE ... HLA-DR3 genes, complement ... self-antigens, activating complement ... Erythematosus #SLE
Atypical HUS - Hemolytic Uremic Syndrome Unlike typical HUS, which is shigatoxin mediated, aHUS is not typically
autoimmune like SLE ... It is complement ... renal, cardiac, pulmonary ... with Eculizumab (complement
Extra-articular and Other Conditions Associated with Joint Pain Eyes • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Spondyloarthropathies, SLE ... retinal exudates) - SLE ... Wilson's disease Pulmonary ... • Pulmonary ... nodules - RA, SLE
Ascites, pericardial effusion, and left pleural effusion on subcostal 4-chamber POCUS echocardiogram Subcostal window in SLE patient.
-chamber POCUS echocardiogram ... Subcostal window in SLE ... effusion #s4c #POCUS #echocardiogram
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