19 results
Causes of Fever of Unknown Origin (FUO) - Differential Diagnosis Algorithm
Neoplasm:
• NHL
• Hodgkin's lymphoma
• Leukemia
• Solid
Causes of Fever ... Differential Diagnosis Algorithm ... Autoimmune: • SLE ... Differential #Diagnosis #Algorithm ... #causes
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
Induced Lupus vs SLE ... 90% - Low complement ... Discontinuation of causal ... 80% - Low complement ... #comparison #table
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
Summary table of ... Allergen-specific lgE causes ... Anaphylaxis, Hay fever ... types #allergy #table ... #classification
Causes of Proteinuria - Differential Diagnosis Algorithm
Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
Causes of Proteinuria ... Differential Diagnosis Algorithm ... • Exercise • Fever ... (MPA) • SLE ... #Causes
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus
Clinical Domains:
 • Constitutional domain: Fever
 • Cutaneous domain: Non-scarring
EULAR/ACR Classification ... Constitutional domain: Fever ... anticoagulant • Complement ... #EULARACR #Classification ... #Criteria #SLE
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
, seasonal hay fever ... antigen, leading to complement ... Complement activation ... Hypersensitivity #Types #Classification ... Diagnosis #Reactions #Table
Causes of Hypernatremia - Differential Diagnosis Algorithm
Hypernatremia - Excess free water loss, Serum Sodium >145 mmol/L
High
Causes of Hypernatremia ... Differential Diagnosis Algorithm ... Osmotic diuresis (see ... ICU patients • Fever ... #Causes
Causes of ileitis beyond Crohn’s disease and infections include systemic disorders -spondyloarthropathies, vasculitides, ischemia, and amyloidosis
Causes of ileitis ... See below for table ... helpful paper complements ... #Differential #Table
Serious Bacterial Illness (SBI):
1) UTI and pyelonephritis
Most common cause of SBI
Accounts for 3-8% of uncharacterized fevers
Female
pyelonephritis Most common cause ... uncharacterized fevers ... presentation Urinalysis: LE ... Diagnosis #Peds #EM #Classification ... #Fever #SBI #SeriousBacterialIllness
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
weight loss, and fever ... anti-Smith Ab, low complements ... Skin Disease Classification ... to: Arthritis, Fever ... RNP antibodies, Complement