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diagnosis differential nephrology acute injury kidney rheumatology glomerulonephritis renal acutekidneyinjury cryoglobulinemia cryoglobulins gammopathy hypertension membranoproliferative mgrs monoclonal mpgn phtn progressive
Guide to Acute Kidney Injury (AKI) What to ask/look for: - HPI, PMH, full ROS
Kidney Injury (AKI ... rhabdo/TLS) Causes ... Glomerulonephritis or vasculitis ... Nephrology #Diagnosis #Algorithm ... #Causes #Differential
Acute Kidney Injury - Classification Prerenal: • Dehydration • Heart failure (a.k.a. cardiorenal syndrome) • Liver failure
Kidney Injury - Classification ... - Small vessel vasculitis ... tubular necrosis (causes ... prolonged prerenal AKI ... EricsMedicalLectures/ #AKI
Acute Kidney Injury (AKI) - Differential Diagnosis Framework Pre-Renal: • Hypovolemia, Cardiorenal, Distributive Shock, HRS, Hypercalcemia, Renal
Kidney Injury (AKI ... Emboli, Thrombosis, Vasculitis ... Medicine @SCVMCMed #AKI ... Diagnosis #nephrology #causes ... #algorithm
Membranoproliferative Glomerulonephritis (MPGN) AKA: Mesangiocapillary GN • Active Urine Sediment (dysmorphic RBC, RBC casts, +/- proteinuria)
Glomerulonephritis (MPGN) AKA ... dysmorphic RBC, RBC casts ... staining (lg + complement ... MGPN • Complement ... immune deposits on EM
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
pathophysiologic causes ... staining): • Low Complement ... Idiopathic • Normal Complement ... Glomerulonephritis #Vasculitis ... differential #diagnosis #algorithm
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis Baseline Investigations: full blood count with differential,
Workup Algorithm ... osmolarity If cause ... Glomerulonephritis / Vasculits ... #Workup #Algorithm ... Diagnosis #nephrology #causes
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Vasculitis and Vasculitides ... When to Consider Vasculitis ... tract, and often causes ... against MPO • Complement ... #rheumatology #classification
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... Cryoglobulins Cause ... • Low serum C4 complement ... • Vasculitis ... diagnosis #types #classification
Clinical Classification of Pulmonary Hypertension 1. Pulmonary arterial hypertension from pulmonary vasculopathy Idiopathic pulmonary arterial hypertension Heritable gene mutations
Clinical Classification ... receptor type 2) - ALKI ... neurofibromatosis, vasculitis ... Hypertension #PHTN #Classification ... #Differential #Causes
Monoclonal Gammopathy of Renal Significance (MGRS) MGRS • MGRS refers to kidney disease caused by nephrotoxic monoclonal immunoglobulins
kidney disease caused ... Clinical Clues: ... guide subtype classification ... tubulopathy) - Complement ... formation causing vasculitis
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