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clinical physicalexam neurology diagnosis ophthalmology differential msk nephrology orthopedics ocular sports test causes algorithm management hyponatremia slitlamp vascular rheumatology outlet
Hypernatremia - Differential Diagnosis Workup Algorithm 1) Check Urine Osmolality: > 600 mOsm/kg - Implies extrarenal mechanism
Hypovolemic: Diuretics, osmotic ... Hypervolemic: Conn syndrome ... , Cushing syndrome ... Algorithm #nephrology #sodium
Pharmacologic Management of Constipation Fiber Laxatives - Bran powder - Psyllium - Methylcellulose - Calcium polycarbophil
Surfactants - Docusate sodium ... - Mineral oil Osmotic ... Tap water - Sodium
Causes of Hypernatremia - Differential Diagnosis Inadequate water intake: • Lack of access to water Extrarenal hypotonic fluid
Diuretics • Osmotic ... Causes #nephrology #sodium
Brugada syndrome with non-sustained VT; sodium channel blocking drugs (e.g. amio, procainamide) can be dangerous here! -
Brugada syndrome ... non-sustained VT; sodium ... amalmattu #Brugada #syndrome
Irritable Bowel Syndrome (IBS) Treatment Algorithm IBS-Constipation: • Constipation: Osmotic laxatives • Abdominal pain: Antispasmodics IBS-Diarrhea: • Diarrhea:
Irritable Bowel Syndrome ... Constipation: Osmotic ... Irritable #Bowel #Syndrome
Inherited Defects in Kidney Tubule Epithelial Cells Renal glucosuria - Na+-dependent glucose cotransporter Cystinuria - Amino acid transporter Bartter
transporter Bartter syndrome ... limb Gitelman syndrome ... tubule Liddle syndrome ... cell epithelial sodium ... of epithelial sodium
Causes of Generalized Edema - Differential Diagnosis Algorithm Overfill (Increased renal sodium retention, Urine Na > 40meq/L)
Increased renal sodium ... • Nephrotic Syndrome ... • Nephrotic syndrome ... Respiratory Distress Syndrome
Hypomagnesemia - Etiologies by Mechanism Decreased GI Uptake - Poor dietary intake (particularly common in alcoholics)
Hypokalemia - Osmotic ... renal Mg wasting syndromes ... - Gitelman syndrome ... - Hungry bones syndrome
Mechanisms of nephron damage in cardiorenal syndrome • Increased renal interstitial pressure • Hypoperfusion • Reduced
in cardiorenal syndrome ... hypertrophy • Sodium ... #cardiorenal #syndrome
Causes of Hypernatremia - Differential Diagnosis Algorithm Hypernatremia - Excess free water loss, Serum Sodium >145 mmol/L High
water loss, Serum Sodium ... administration • Osmotic
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