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management rheumatology sle treatment classification druginduced erythematosus systemic acromegaly algorithm antiphospholipid apls cerebritis cns comparison cryoglobulinemia cryoglobulins dementia dermatology differential
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
(SLE) - Diagnosis ... 40, F:M 9:1 • Clinical ... • Immunologic Workup ... Positive in 60-80% of cases ... Erythematosus #Diagnosis
Major neurocognitive disorders (MNCD): Diagnosis and workup 1) Clinical diagnosis Cognitive impairment + loss of autonomy 2)
1) Clinical diagnosis ... MRI, iADL scale, ... Alzheimer - 1st cause ... Aphaso-apraxo-agnosia syndrome ... Dementia - 2nd cause
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... • Immunologic Workup ... 40, F:M 9:1 • Clinical ... • Immunologic Workup ... #diagnosis #management
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE) Clinical ... Demyelinating Syndrome ... autoantibodies that will cause ... permeability Diagnosis ... #cerebritis #diagnosis
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... Cryoglobulins Cause ... : • Clinical triad ... Labs/Diagnosis: ... (e.g. systemic lupus
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
Rheumatic pain Clinical ... : • A clinical ... diagnosis • Rule ... out other causes ... - MRI: inflammation
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook Clinical Presentation: • Classic Acromegaly: frontal
GrepMed Handbook Clinical ... Beckwith Wiedemann syndrome ... and Workup: • ... • Pituitary MRI ... or refractory cases
Antiphospholipid Syndrome (APLS) Testing - Hypercoagulable Workup Algorithm INDICATIONS FOR TESTING: • Vascular thrombosis
- 1 or more clinical ... maternal chromosomal causes ... excluded Testing: • Lupus ... #Algorithm #diagnosis ... #hematology
Drug Induced Lupus (DIL) • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
to 1:1 F:M • Clinical ... • Immunologic Workup ... Discontinuation of causal ... #DIL #rheumatology ... #diagnosis #treatment
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
HLH is a critical ... caused by uncontrolled ... or triggers) is crucial ... Clinical Presentation ... #Management #Hematology
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