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neurology differential rheumatology oncology treatment algorithm pathophysiology anemia barre causes guillain leukemia ophthalmology aflp aplastic chronic classification disease disorders encephalopathy
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
, CLL Acute leukemias ... ALL (Acute Lymphoblastic ... ) CLL Symptoms: ... #Leukemia #Hematology ... #Oncology #Diagnosis
Guillain-Barre Syndrome An acute polyneuropathy (disorder Of the peripheral nervous System). Symptoms are Often symmetrical and progress Over
Guillain-Barre Syndrome ... An acute polyneuropathy ... Symptoms are Often ... #Diagnosis #Neurology ... #Signs
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
with no early symptoms ... Physical Exam/Signs ... Diagnosis: • ... ’s lymphoma or acute ... workup #oncology #hematology
Aplastic Anemia - Illness Script Signs and symptoms: • Recurrent infections from neutropenia • Mucosal bleeding from
Illness Script Signs ... and symptoms: ... progress to MDS or acute ... #management #treatment ... #hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... transformation to acute ... Allogeneic stem cell ... Myelodysplastic #Syndrome ... #hematology #oncology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Dehydration • Symptoms ... - ACS, AKI, acute ... WBC >100k, + lab signs ... #TLS #diagnosis ... #management #hematology
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
- Differential Diagnosis ... Thrombocytosis): • Acute ... Myelodysplastic syndrome ... myeloid leukemia (CML ... #Causes #hematology
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Overwhelming clinical syndrome ... : HLH signs and ... symptoms can mimic ... presents as an acute ... #hematology
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP) Three syndromes in
TTP/HUS, HELLP Syndrome ... and Acute Fatty ... the critically ill ... AFLP #obstetrics #hematology ... #diagnosis #table
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... • Induce blast cell ... : >3 symptoms, or ... Differentiation #Syndrome ... #management #hematology
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