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rheumatology differential dermatology systemic erythematosus lupus symptoms antibodies autoantibodies autoimmune myositis vasculitis algorithm ana antimda5 antimda5dm antinuclear antinxp2 antinxp2dm associations
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
Joint Pain Rash ... infection Malar rash ... • SLE • Human ... IBD • RA • SLE ... #differential #diagnosis
Autoimmune Myositis Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
Dermatomyositis ... can present with rash ... , Shaw sign, holster ... Can also see mechanics ... #rheumatology
Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
- Drug-induced SLE ... Polymyositis / Dermatomyositis ... Primary biliary cirrhosis ... Associations #diseases #diagnosis ... #table #rheumatology
ANTI-MDA5 DERMATOMYOSITIS Cutaneous manifestations: • Periorbital heliotrope (blue-purple) rash with edema • Erythematous rash on the face, or the
(blue-purple) rash ... • Erythematous rash ... chest (in a V-sign ... Inverse Gottron’s sign ... dermatology #diagnosis
Nail Disorders secondary to Systemic Diseases Nail Fold Abnormality • SLE • Scleroderma • Dermatomyositis Koilonychia - Spoon-shaped
Abnormality • SLE ... Scleroderma • Dermatomyositis ... discoloration) • Liver cirrhosis ... Systemic #Secondary #dermatology ... #Differential #Diagnosis
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Systemic Lupus (SLE ... Photosensitivity, Butterfly rash ... erythematosus #signs ... #symptoms #diagnosis ... #rheumatology
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
69% - Malar rash ... involvement 3% SLE-Related ... Lupusreference #SLE ... autoantibodies #signs ... #differential #rheumatology
Systemic Lupus Erythematosus (SLE) - Typical Signs/Symptoms Alopecia, Fever, Malar rash, Photosensitivity, Adenopathies, Lupus pneumonia, Pleurisy, Pancreatitis,
Erythematosus (SLE ... ) - Typical Signs ... , Fever, Malar rash ... , Oral ulcers, Rash ... #diagnosis #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Differential Diagnosis ... Still disease, dermatomyositis ... Malignancy (e.g. hematologic ... vein thrombosis Hematologic ... Erythematosus #Diagnosis
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
erythematosus (SLE ... , Polymyositis/Dermatomyositis ... Primary Biliary Cirrhosis ... ANA #patterns #rheumatology ... #diagnosis #differential
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