23 results
Manifestations of IgG4-related disease by organ system.
 The most common primary disease features are indicated in
The most common primary ... disease features ... Organs #Systems #Diagnosis ... #Hematology #Signs ... #Symptoms
Osteoporosis: Pathogenesis and risk factors

 • Age > 30 (post-peak bone mass)
 • Post-menopausal women ->
liver or kidney disease ... Corticosteroid use • Primary ... #Osteoporosis #pathophysiology ... #signs #symptoms ... #diagnosis
Primary Biliary Cirrhosis - Diagnosis Algorithm
Symptoms: Fatigue, Pruritus, Right upper quadrant discomfort
Signs: Jaundice, Xanthelasmata, Hepatomegaly
Associated history:
Primary Biliary ... Algorithm Symptoms ... Associated history: Symptoms ... of autoimmune disease ... #Algorithm #hepatology
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm

ALP:
 - Enzymes that catalyze hydrolysis of organic phosphate
- Differential Diagnosis ... Most common symptoms ... - Bone symptoms ... - Drugs - Primary ... #Algorithm #hepatology
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings
• Primary Sjögren's is a solitary process whereas secondary Sjögren's
other autoimmune diseases ... with systemic diseases ... Sjogrens #Syndrome #Pathophysiology ... #Diagnosis #Signs ... #Symptoms
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
Primary Biliary ... 65 years PBC Pathophysiology ... PBC Signs and Symptoms ... but elevated as disease ... #workup #hepatology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
15% of AIHA Primary ... (Cold-induced symptoms ... Diagnosis: • hemolytic ... hemolytic #anemia #hematology ... #diagnosis
Mycoses

HISTOPLASMOSIS
• Inhalation of conidia → Yeast → travel to lymph nodes → spread in body
• Bird
: • Primary pulmonary ... extrapulmonary disease ... or meningitic disease ... Aspergillosis Pathophysiology ... ) #Mycoses #InfectiousDiseases
The 6 C’s of Primary Sclerosing Cholangitis (PSC)
PSC is a chronic, cholestatic, immune-mediated disease characterized by
The 6 C’s of Primary ... asymptomatic at diagnosis ... Care focuses on symptom ... #Cholangitis #diagnosis ... management #summary #Hepatology
Bipolar Disorder: Pathogenesis and Clinical Findings
 • Disruption of emotional homeostasis
 • Oscillation between mood states
variability in disease ... normal mood - Primary ... MoodDisorders #Diagnosis ... #Pathophysiology ... #Signs #Symptoms