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diagnosis differential management erythematosus lupus ana antibodies antinuclear signs vasculitis anca antibody antineutrophil behcet blurry causes classification conditions cryofibrinogenemia disease
Blurry Vision - Differential Diagnosis Framework Anatomical Approach to Eye Disease: 1. Lids/Lashes 2. Extraocular Muscles/Motility 3. Conjunctiva/Sclera 4. Cornea 5. Anterior
of Systemic Medications ... - Retinal vein occlusions ... ’s syndrome • ... (Retinal vein occlusions ... hyperviscosity syndrome
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Lupus (SLE) General ... loss (50%) Eye: Sjögrens ... Demyelinating syndromes ... #signs #symptoms ... #diagnosis #rheumatology
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
severe disease & renal ... heart block • Sjogren ... syndrome Anti-UI-ribonucleoprotein ... polymyositis overlap syndrome ... Summary #diagnosis #rheumatology
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
context of other symptoms ... erythematosus (SLE ... ), Sjogren's Syndrome ... Syndrome, Myositis ... ANA #patterns #rheumatology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
Systemic disease ... disease (SVC/IVC occlusion ... Oral aphthae : SLE ... • Arthritis: SLE ... #rheumatology #
Extra-articular and Other Conditions Associated with Joint Pain Eyes • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Cytoid bodies (retinal ... system • Entrapment ... Genitourinary system ... enlargement - Sjögren's ... differential #diagnosis #rheumatology
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
antibodies) • Systemic ... in drug-induced SLE ... 70% of cases • Sjögren ... syndrome 1. ... antibodies #diagnosis #rheumatology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Sjogren's Syndrome ... overlaps with RA, SLE ... enlargement Sjogren's ... gland) biopsy • Ocular ... #Syndrome #Rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Erythematous, macular ... dermatomyositis, Sjogren ... Non-autoimmune rheumatologic ... Induced Lupus: • Symptoms
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
Cryofibrinogenemia Symptoms ... processes: • Systemic ... pulmonary emboli, and ocular ... thrombi including retinal ... Antiphospholipid syndrome
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