16 results
diagnosis management oncology syndrome dermatology hemophagocytic hlh leukemia lymphohistiocytosis adultonset algorithm apml cardiology chronic classification cll comparison damage differential differentiation
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Clinical triad: Fever ... hemopathies, solid cancers ... hepatitis • Pulmonary ... diagnosis #management #treatment ... #rheumatology
TRALI vs TACO - Transfusion Reactions TRALI: • Epidemiology: 0.1% of transfused patientsl • Risk factors: Critical
without other cause ... : 33% • Treatment ... At least 3 of (Acute ... , and CXR with pulmonary ... Transfusion #Reactions #hematology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
• Clinical: fever ... B-LNH), solid cancers ... Drugs, Unknown cause ... inhibitors under evaluation ... #summary #rheumatology
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Sweet Syndrome Acute ... Causes: - Idiopathic ... , breast CA - Hematologic ... cancer such as ... Treatment: - Systemic
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Triggers: ATRA treatment ... : • Common: fever ... Imaging: CXR- pulmonary ... Renal Failure Treatment ... diagnosis #management #hematology
Hemophilia - Diagnosis and Management Diagnosis: • Consistent bleeding history (unless screening for disease in family members
normal in mild cases ... - Acute Bleeding ... by a hemophilia treatment ... center. ... #hematology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
high WBC count cause ... - 80% have fever ... - ACS, AKI, acute ... organ damage • Treatment ... diagnosis #management #hematology
Acute Recurrent Pericarditis = recurrence of Acute Pericarditis (AP) after free interval >4-6 weeks without symptoms, >1/4
symptoms, >1/4 of AP cases ... RED FLAGS: Fever ... Systemic symptoms: pulmonary ... manifestations, TREATMENT ... #rheumatology #
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Leukemia - Summary Cancer ... Lymphadenopathy • Fevers ... microglobulin Treatment ... ’s lymphoma or acute ... workup #oncology #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
-> AML: Blast crises ... Headaches, bone pain, fever ... lymphoid organs When Cancer ... Lymphadenopathy • HSM • Fevers ... #Leukemia #Hematology
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