9 results
Causes of Ascites
Normal Peritoneum
Portal hypertension (SAAG > 1.1 g/dL)
  1. Hepatic congestionl
Liver disease ... - Cirrhosis ... fibrosis - Acute ... fatty liver of ... #differential #hepatology
Serum Ascites Albumin Gradient (SAAG) - Differential Diagnosis
High albumin gradient (>1.1 g/dl):
 - Cirrhosis	
 - Alcoholic
Gradient (SAAG) ... >1.1 g/dl): - Cirrhosis ... - Massive liver ... Veno-occlusive disease - Acute ... fatty liver of
Portal Hypertension - Differential Diagnosis
Portal Pressure = the pressure difference between the pressure in the portal
of portal HTN: ascites ... (SAAG>I.I), esophageal ... portal HTN: • Ascites ... /acute hepatitis ... sarcoidosis) • Liver
Indications for Albumin for Management of Cirrhosis
 • Large volume paracentesis (>5 liter) - 8g per
Management of Cirrhosis ... of ascites removed ... • Acute kidney ... Indications #Management #Cirrhosis ... #treatment #hepatology
Causes of Ascites - Differential Diagnosis Algorithm
Portal Hypertension - Prehepatic:
 • Portal vein thrombosis
 • Splenic
Causes of Ascites ... - Hepatic: • Cirrhosis ... Infiltrative disease • Acute ... liver failure ... Diagnosis #Algorithm #Hepatology
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Acute Fatty Liver ... Pregnancy (AFLP) Pathophysiology ... headache, malaise) → Acute ... develops (DIC, ascites ... #Pregnancy #hepatology
Acute-phase Reactants Synthesized in the Liver 
Positive acute-phase reactants (concentrations increase with acute inflammation)
 - Immune-related
Acute-phase Reactants ... Positive acute-phase ... increase with acute ... Ferritin Negative acute-phase ... decrease with acute
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
malignancy (Especially acute ... protein C and S Pathophysiology ... or venipuncture sites ... DIC • Severe Liver ... treatment #management #hematology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
first step in evaluation ... Viral infections (acute ... Sarcoidosis) • Liver ... disease: Cirrhosis ... inflammation (acute