20 results
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
→ Refer to hematology ... for workup, including ... , deficiency anemia ... Malignancy: Metastatic cancer ... Diagnosis #Algorithm #hematology
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Decreased WBCs
 - Decreased/NormaI
Causes of Anemia ... RA, SLE, PRV, Chronic ... Normal RBCs • Acute ... Inflammation • Cancer ... Algorithm #Causes #Hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Diagnosis and Workup ... test, ANA (e.g., SLE ... changes), high MCV anemia ... - Bone marrow evaluation ... #hematology
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... ): SS, SC, SE, Sβ ... ARUPLabs #Hemolytic #Anemia ... Diagnosis #Algorithm #workup ... #hematology #testing
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Erythematosus (SLE ... • Immunologic Workup ... • Evolution: ... Chronic disease ... Management #Summary #rheumatology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Hemolytic anemia ... - APLS • Acute ... Associated - SLE ... Differential #Diagnosis #hematology ... #rheumatology #
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor
The maturation factor is
Index < 2: • Anemia ... Chronic kidney disease ... infiltration (e.g. cancer ... Index > 3: • Acute ... Production #Index #hematology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Classification: • Acute ... Pleural effusions • Acute ... lymphopenia, low PLT • Anemia ... • Cervical cancer ... Erythematosus #Diagnosis #Rheumatology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
• Immunologic Workup ... • Immunologic Workup ... • Evolution: ... Chronic disease ... comparison #table #rheumatology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
TTP - Laboratory Evaluation ... hallmark for the disease ... result in severe anemia ... ThromboticThrombocytopenicPurpura #Diagnosis #Workup ... #Hematology