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diagnosis differential liver algorithm causes management transaminitis hepatitis hepatorenal hrs laboratory leukemia oncology testing aclf aih anemia arthritis autoimmune bleeding
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework Mild (<100-500): • NAFLD • Cirrhosis •
Function Tests (LFTs ... Cirrhosis • Chronic ... Hepatopathy • Acute ... Drug-induced liver injury ... Differential #Diagnosis #hepatology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
→ Refer to hematology ... : Acute blood loss ... , Acute hemolysis ... Severe trauma, Acute ... Diagnosis #Algorithm #hematology
Patterns of Liver Injury Transaminase Levels: > 50x normal - Ischemic Hepatitis > 20x normal
Patterns of Liver Injury ... > 20x normal - Acute ... 5-10x normal - Chronic ... Patterns #Liver #Injury ... #hepatology #LFTs
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Hepatocellular - Check Acute ... Mixed - Check Acute ... Imperative to Identify Acute ... Cirrhosis: > 1 • Acute ... #differential #Hepatology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... underlying liver disease ... Drug-Induced Liver Injury ... EmoryGastroHep #ACLF #Acute ... Failure #Cirrhosis #Hepatology
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
Causes of Acute ... Autoimmune hepatitis, Acute ... obstruction, HELLP Syndrome ... Diagnosis #Causes #Acute ... #algorithm #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Acute Liver Injury ... Vascular Causes of Acute ... Hepatocellular Acute ... Cholestatic Acute ... diagnosis #algorithm #hepatology
Algorithm for the Evaluation of Chronic Diarrhea (< 7 days) Exclude: 1. Causes of acute diarrhea 2. Lactose intolerance 3.
Algorithm for the Evaluation ... of Chronic Diarrhea ... Causes of acute ... Systemic disease ... management #algorithm #workup
Diagnostic Framework for Anemia (Morphological Approach - MCV) Low MCV - <80fL - "Microcytic" • Iron deficiency
kidney disease, ... Acute blood loss ... Alcohol use, Liver disease ... Myelodysplastic syndrome ... diagnosis #causes #hematology
Hepatorenal Syndrome (HRS) - Diagnostic Criteria HRS-AKI (Acute: previously known as HRS Type 1) • ↑ Creatinine
Hepatorenal Syndrome ... Criteria HRS-AKI (Acute ... structural kidney injury ... HRS-NAKI (Non-Acute ... HRSAKI #HRSNAKI #hepatology
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