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Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... those with CLD (± cirrhosis ... months without treatment ... disease, liver ... EmoryGastroHep #ACLF #Acute
Causes of Severe Acute Liver Injury
 - Ichemic hepatitis
 - Acute biliary obstruction
 - Drug-Induced liver
Acute Liver Injury ... hepatitis - Acute ... hepatitis - Wilson disease ... LiverInjury #Severe #Acute ... #Hepatology #Diagnosis
Differential Diagnosis and Evaluation of Hyponatremia:
1) Identification of onset (acute vs. chronic)
2) Presence of symptoms (HA,
Diagnosis and Evaluation ... Identification of onset (acute ... history (cardiac, liver ... , renal disease) ... Differential #Algorithm #Ddxof
Portal Hypertension - Differential Diagnosis
Portal Pressure = the pressure difference between the pressure in the portal
/acute hepatitis ... • Infiltrative diseases ... sarcoidosis) • Liver ... Veno-occlusive disease ... #hepatology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Diagnosis and Workup ... disease, decrease ... disease), HBsAg ... - Bone marrow evaluation ... #Workup #hematology
Hepatobiliary Manifestations of Sickle Cell Disease
Acute sickle cell hepatic crisis:
 • Fever, acute onset RUQ pain,
Acute sickle cell ... crisis: • Fever, acute ... Supportive with treatment ... of SCD crisis Acute ... progressing to acute
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
Causes of Acute ... Autoimmune hepatitis, Acute ... Differential #Diagnosis #Causes ... #Acute #algorithm ... #hepatology
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
Causes of Thrombocytosis ... Infectious: • Acute ... disorders • Celiac disease ... effect following treatment ... Diagnosis #Algorithm #Causes
Indications for Albumin for Management of Cirrhosis
 • Large volume paracentesis (>5 liter) - 8g per
Management of Cirrhosis ... ) - 8g per liter ... ascites removed • Acute ... Indications #Management #Cirrhosis ... #treatment #hepatology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
for workup, including ... : Acute blood loss ... , Acute hemolysis ... infections, TB, Acute ... Severe trauma, Acute