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diagnosis algorithm differential leukemia management mds myelodysplastic rheumatology apml arthritis cancer cell chronic dermatology differentiation disease erythematosus gap globulin laboratory
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... cytopenias (usually anemia ... transformation to acute ... Allogeneic stem cell ... #hematology #oncology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
, CLL Acute leukemias ... ALL (Acute Lymphoblastic ... Lymphadenopathy AML (Acute ... - infiltrates (anemia ... Blasts APML (Acute
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
: Acute blood loss ... , Acute hemolysis ... , deficiency anemia ... infections, TB, Acute ... Severe trauma, Acute
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
• Neutropenia, anemia ... microglobulin Treatment ... ’s lymphoma or acute ... Leukemia #diagnosis #workup ... #oncology #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... factor (GCSF) treatments ... Workup: • Complete ... #diagnosis #hematology ... #oncology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Presentation: Subacute-Acute ... • Rare: DAH, acute ... , Anaphylaxis, Acute ... diagnosis #management #hematology ... #oncology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Classification: • Acute ... Malignancy (e.g. hematologic ... Pleural effusions • Acute ... vein thrombosis Hematologic ... lymphopenia, low PLT • Anemia
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Acute febrile ... , breast CA - Hematologic ... - Lupus - Leukemia ... Treatment: - Systemic ... #oncology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... joint • Systemic lupus ... Screening Tests for All ... the presence of anemia ... Screening Tests for Acute
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Albumin > 4) Work-up ... first step in evaluation ... Viral infections (acute ... anemia • Other ... inflammation (acute
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