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diagnosis differential rheumatology causes sle management classification hematology algorithm allergy comparison hypersensitivity inflammatory oncology pericarditis reactions signs symptoms syndrome table
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... • Immunologic Workup ... life-threatening • Treatment ... : Chronic disease ... #Systemic #Erythematosus
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Systemic Lupus Erythematosus ... Manifestations: - Arthritis ... - Hemolytic anemia ... sclerosis, Still's disease ... #Lupus #Erythematosus
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Classification: • Acute ... lupus erythematosus ... lymphopenia, low PLT • Anemia ... #Lupus #Erythematosus
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Lupus (SLE) General ... of hip (rare), Arthritis ... pain (20%) Renal disease ... ) Blood (75%): Anemia ... #erythematosus #
Inflammatory Joint Pain - Differential Diagnosis Algorithm Monoarticular • Gout (Podagra, Tophi) • Pseudogout • Early
• Rheumatoid Arthritis ... • Systemic Lupus ... Erythematosus ... Rheumatic Fever Acute ... • Psoriatic Arthritis
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
• Systemic lupus ... erythematosus ... lupus erythematosus ... with leukopenia, anemia ... Treatment: • Corticosteroids
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Constitutional symptoms, Arthritis ... • Immunologic Workup ... months to years) Systemic ... Lupus Erythematosus ... : Chronic disease
BEE Syndromes - Immune-mediated conditions affecting the brain, eye, and ear Visual or auditory symptoms in conjunction
central nervous system ... diagnosis and treatment ... Cogan syndrome • Acute ... Sjögren syndrome • Systemic ... lupus erythematosus
Causes of Pericarditis - Differential Diagnosis Algorithm Viral: • Coxsackie • Echovirus • Adenovirus • Epstein-Barr virus
• Rheumatoid arthritis ... • Systemic lupus ... erythematosus ... connective tissue disease ... Metabolic: • Uremia
Hypersensitivity: Summary Type I Hypersensitivity: • Immunological Mediator: lgE • Immunological Target: Allergen Molecules • Ex: Antibiotic
Autoimmune Hemolytic anemia ... Gravis, Graves' Disease ... complexes • Ex: Systemic ... Lupus Erythematosus ... , Reactive Arthritis
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