29 results
Causes of Severe Aortic Regurgitation - Differential Diagnosis
Acute:
 • Leaflet: Traumatic Rupture, Acute Infective Endocarditis, Acute
Inflammatory: Lupus ... , Crohn Disease ... , Behcet Syndrome ... Ehlers-Danlos Syndrome ... Degenerative: Systemic
BEE Syndromes - Immune-mediated conditions affecting the brain, eye, and ear

Visual or auditory symptoms in conjunction
central nervous system ... and less common diseases ... diagnosis and treatment ... • Acute disseminated ... • Systemic lupus
Connective tissue disease-associated interstitial lung diseases

LIP: lymphoid interstitial pneumonia. NSIP: nonspecific interstitial pneumonia. OP: organizing pneumonia.
AIP: acute interstitial ... PSS: Sjogren syndrome ... RA: rheumatoid arthritis ... SLE : systemic ... lupus.
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Lupus (SLE) General ... of hip (rare), Arthritis ... Demyelinating syndromes ... pain (20%) Renal disease ... ) Blood (75%): Anemia
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Systemic lupus ... idiopathic arthritis ... lupus erythematosus ... with leukopenia, anemia ... Treatment: • Corticosteroids
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... • Immunologic Workup ... life-threatening • Treatment ... : Chronic disease ... #Systemic #Erythematosus
Inflammatory Joint Pain - Differential Diagnosis Algorithm 
Monoarticular
 • Gout (Podagra, Tophi)
 • Pseudogout
 • Early
• Rheumatoid Arthritis ... • Systemic Lupus ... Sicca) Syndrome ... Rheumatic Fever Acute ... • Psoriatic Arthritis
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Classification: • Acute ... Pleural effusions • Acute ... Neuropsychiatric systemic ... lymphopenia, low PLT • Anemia
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
Constitutional symptoms, Arthritis ... • Immunologic Workup ... months to years) Systemic ... • Immunologic Workup ... : Chronic disease
Interstitial Lung Diseases (ILD)
Exposure-Related ILD (a.k.a. extrinsic allergic alveolitis): 
 • Hypersensitivity pneumonitis, Farmer's lung, Bird
: • Systemic sclerosis ... , Rheumatoid arthritis ... Polymyositis-dermatomyositis, Lupus ... pneumonia (DIP), Acute ... Churg Strauss syndrome