15 results
Hepatobiliary Manifestations of Sickle Cell Disease
Acute sickle cell hepatic crisis:
 • Fever, acute onset RUQ pain,
Disease Acute ... crisis: • Fever, acute ... Supportive with treatment ... of SCD crisis Acute ... hepatomegaly and anemia
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
: Acute blood loss ... , Acute hemolysis ... , deficiency anemia ... infections, TB, Acute ... Severe trauma, Acute
Aplastic Anemia - Illness Script
Signs and symptoms:
 • Recurrent infections from neutropenia
 • Mucosal bleeding from
Treatment: • Consider ... stem cell transplant ... progress to MDS or acute ... diagnosis #management #treatment ... #hematology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
• Neutropenia, anemia ... microglobulin Treatment ... ’s lymphoma or acute ... Leukemia #diagnosis #workup ... #oncology #hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
= funny-shaped cells ... cytopenias (usually anemia ... transformation to acute ... Allogeneic stem cell ... #hematology #oncology
Anemia Diagnostic Algorithm

Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95
Mean corpuscular (cell ... Red cell distribution ... High in acute blood ... Algorithm #Diagnosis #Workup ... #Hematology #Microcytic
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Classification: • Acute ... Angioimmunoblastic T-cell ... Pleural effusions • Acute ... lymphopenia, low PLT • Anemia ... : • Chronic B-cell
HEART Score – A Tool For the ED The HEART score is an excellent tool that
with possible Acute ... admission for further workup ... and treatment versus ... identifying low risk as well ... Stratification #ChestPain
Approach to Joint Pain - Diagnostic Framework

1) Chronicity
2) Inflammatory vs Non-Inflammatory
3) Number of Joints Involved

1) Chronicity:
Chronicity: • Acute ... infections (bacterial), acute ... Send for cell count ... • Acute = Viral ... #approach #workup
IgG4-Related Disease
Clinical history:  Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor
4 phenotypes:
 •
hypergammaglobulinemia, ↑ acute ... increased IgG4+ cells ... " Treatment: ... management #phenotypes #workup ... #treatment #rheumatology