11 results
Algorithm for the Evaluation and Management of Sickle Cell Crises
Clinical Manifestations and Management

#Diagnosis #Management #Hematology #SickleCell
Algorithm for the Evaluation ... Crises Clinical Manifestations ... Diagnosis #Management #Hematology ... #Workup #Algorithm ... #Ddxof
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
1 • Clinical Manifestations ... • Immunologic Workup ... : - ANA > ... • Evolution: ... Management #Summary #rheumatology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
• Immunologic Workup ... : - ANA > ... • Immunologic Workup ... • Evolution: ... #table #rheumatology
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Systemic Lupus Erythematosus ... Antinuclear (ANA ... Associated with skin manifestations ... #Systemic #Lupus ... Summary #diagnosis #rheumatology
Top 10 situations when to think about lupus
1) Inflammatory joint pain (especially in the wrists and
to think about lupus ... children (pediatric SLE ... to unexplained manifestations ... #diagnosis #sle ... erythematosus #rheumatology
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
- Diagnosis Manifestations ... involvement 3% SLE-Related ... Auto-Antibodies: - ANA ... Lupusreference #SLE ... #differential #rheumatology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Diagnosis and Workup ... function test, ANA ... (e.g., SLE), anti-phospholipid ... - Bone marrow evaluation ... #hematology
Drug Induced Lupus (DIL)
 • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
is rare in DIL, SCLE-DIL ... • Immunologic Workup ... : - ANA > ... cutaneous-DIL • Evolution ... #DIL #rheumatology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of
Rheumatology Workup ... joint • Systemic lupus ... thus, a negative ANA ... Arthritis #laboratory #workup ... diagnosis #testing #Rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
< 30 years - Aorta ... branches • GCA: - Aorta ... such as systemic lupus ... vasculitis, and SLE ... differential #diagnosis #rheumatology